Contrast-enhanced CT-based Deep Learning Model for Preoperative Prediction of Disease-free Survival (DFS) in Localized Clear Cell Renal Cell Carcinoma (ccRCC)

NCT ID: NCT06088134

Last Updated: 2025-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-01

Study Completion Date

2025-08-01

Brief Summary

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This study aims to preoperatively predict DFS of patients with localised ccRCC using a deep learning prognostic model based on enhanced contrast CT images, validate it's predictive ability in multicentre data and compare it's predictive ability with traditional models.

Detailed Description

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Conditions

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Clear Cell Renal Cell Carcinoma Prognostic Cancer Model Recurrent Renal Cell Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Non-recurrence group

No interventions assigned to this group

Recurrence group

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* underwent partial/radical nephrectomies
* histologically diagnosed as ccRCC
* with complete clinical data and preoperative CT image data

Exclusion Criteria

* with incomplete clinic-pathological data
* lack of preoperative contrast-enhanced CT images or the image quality was unsuitable for analysis
* who received pre-surgery neoadjuvant or adjuvant therapies
* with multiple renal tumors or/and had synchronous metastasis
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mingzhao Xiao

OTHER

Sponsor Role lead

Responsible Party

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Mingzhao Xiao

Urology Department

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Yingjie Xv

Chongqing, Chongqing Municipality, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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Yingjie Xv

Role: primary

83-18725891425

References

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Xv Y, Wei Z, Jiang Q, Zhang X, Chen Y, Xiao B, Yin S, Xia Z, Qiu M, Li Y, Tan H, Xiao M. Three-dimensional deep learning model complements existing models for preoperative disease-free survival prediction in localized clear cell renal cell carcinoma: a multicenter retrospective cohort study. Int J Surg. 2024 Nov 1;110(11):7034-7046. doi: 10.1097/JS9.0000000000001808.

Reference Type DERIVED
PMID: 38896853 (View on PubMed)

Other Identifiers

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DL-ccRCC

Identifier Type: -

Identifier Source: org_study_id

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