Clinical Efficacy of Hybenix vs Chlosite Gels in Peri-implantitis
NCT ID: NCT06083246
Last Updated: 2025-11-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
40 participants
INTERVENTIONAL
2023-10-10
2025-11-10
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
After the peri-implant evaluation, patients will undergo supragingival and subgingival professional oral hygiene of both arches performed with ultrasonic instrumentation with PEEK inserts, manual instrumentation with teflon curettes and air polishing with glycine powder.
After that, the sample will be randomly divided into 2 groups based on thein-office assigned treatment:
* Chlosite® gel application in the peri-implant sulcus
* Hybenix® gel application for 30 s followed by rinsing of the peri-implant sulcus.
The study will last 9 months. Patients will be visited at: T0, after 1 month from T0 (T1), after 3 months (T2), after 6 months (T3) and after 9 months (T4).
In each time frame, indexes collection and nonsurgical debridement will be performed.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Domiciliary Use of Hyaluronic Acid Gel Solutions vs Domiciliary Use of Chlorhexidine Mouthwash 0,20% for the Management of Peri-implant Mucositis Sites
NCT05312593
Chlorhexidine Gel and Peribioma Periogel Use in Peri-implant Mucositis Sites: a Split-mouth Randomized Clinical Trial.
NCT04899986
Efficacy of a Xanthan-based Chlorhexidine Gel in the Treatment of Peri-implant Mucositis
NCT07047261
Natural Bioactive Gel for Peri-Implantitis
NCT07088679
Impact of Oral Hygiene Gels on Peri-implant Mucositis
NCT03243591
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Patients responding to the inclusion criteria will be included in the study. The following peri-implant indexes will be collected:
* BOP (Bleeding On Probing)
* GBI (Gingival Bleeding Index)
* Marginal Mucosal Conditions (swelling and erythema)
* Suppuration
* Mucosal margin migration
* PPD (Probing Pocket Depth)
* PI (Plaque Index)
* BS (Bleeding Score)
* Radiographic bone loss
After the peri-implant evaluation, patients will undergo supragingival and subgingival professional oral hygiene of both arches performed with ultrasonic instrumentation with PEEK inserts, manual instrumentation with teflon curettes and air polishing with glycine powder.
After that, the sample will be randomly divided into 2 groups based on thein-office assigned treatment:
* Chlosite® gel application in the peri-implant sulcus
* Hybenix® gel application for 30 s followed by rinsing of the peri-implant sulcus.
The study will last 9 months. Patients will be visited at: T0, after 1 month from T0 (T1), after 3 months (T2), after 6 months (T3) and after 9 months (T4).
In each time frame, indexes collection and nonsurgical debridement will be performed.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Hybenix gel
Clinical application of Hybenix gel.
Hybenix gel
Clinical application of Hybenix gel after professional dental hygiene of peri-implant mucositis sites.
Chlosite
Clinical application of Chlosite gel.
Chlosite gel
Clinical application of Chlosite gel after professional dental hygiene of peri-implant mucositis sites.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Hybenix gel
Clinical application of Hybenix gel after professional dental hygiene of peri-implant mucositis sites.
Chlosite gel
Clinical application of Chlosite gel after professional dental hygiene of peri-implant mucositis sites.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* Patients suffering from psychological, neurological or psychiatric disorders
* Patients suffering from systemic, metabolic or autoimmune diseases
* Pregnant women
18 Years
70 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Pavia
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Andrea Scribante
Associate Professor, Principal Investigator
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Andrea Scribante, DDS, PhD, MSc
Role: PRINCIPAL_INVESTIGATOR
University of Pavia
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Unit of Dental Hygiene - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia
Pavia, Lombardy, Italy
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2023-IMPLGEL
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.