Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
176 participants
INTERVENTIONAL
2023-08-31
2024-04-02
Brief Summary
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VK2735 or matched placebo will be administered once weekly.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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VK2735 (Placebo)
Placebo
Placebo
Placebo comparator
VK2735 (Dose #1)
VK2735 is a peptide GLP-1 and GIP dual agonist
VK2735
VK2735 is a peptide GLP-1 and GIP dual agonist
VK2735 (Dose #2)
VK2735 is a peptide GLP-1 and GIP dual agonist
VK2735
VK2735 is a peptide GLP-1 and GIP dual agonist
VK2735 (Dose #3)
VK2735 is a peptide GLP-1 and GIP dual agonist
VK2735
VK2735 is a peptide GLP-1 and GIP dual agonist
VK2735 (Dose #4)
VK2735 is a peptide GLP-1 and GIP dual agonist
VK2735
VK2735 is a peptide GLP-1 and GIP dual agonist
Interventions
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VK2735
VK2735 is a peptide GLP-1 and GIP dual agonist
Placebo
Placebo comparator
Eligibility Criteria
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Inclusion Criteria
2. Body mass index (BMI) ≥30 kg/m2 OR ≥27 kg/m2 with at least one weight-related co-morbid condition (treated or untreated), and BMI \<50 kg/m2
Exclusion Criteria
2. Self-reported body weight change of 5% or more within 3 months of screening
3. Current or past diagnosis of diabetes mellitus (including type 1, type 2, gestational)
4. Current or past diagnosis of chronic pancreatitis
5. Calcitonin ≥20 ng/L measured by central laboratory at screening (individuals with elevated calcitonin at initial screening may be re-screened)
6. Any GLP-1 receptor agonist or GLP-1/GIP dual agonist within 6 months of Screening
7. Any prescription or over-the-counter medications intended for weight loss within 6 months of screening
18 Years
ALL
No
Sponsors
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Viking Therapeutics, Inc.
INDUSTRY
Responsible Party
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Locations
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Viking Clinical Site #119
Birmingham, Alabama, United States
Viking Clinical Site #114
Long Beach, California, United States
Viking Clinical Site #110
Los Angeles, California, United States
Viking Clinical Site #113
Tustin, California, United States
Viking Clinical Site #116
Clearwater, Florida, United States
Viking Clinical Site #106
Clearwater, Florida, United States
Viking Clinical Site #112
Jacksonville, Florida, United States
Viking Clinical Site #105
Ocoee, Florida, United States
Viking Clinical Site #107
Port Orange, Florida, United States
Viking Clinical Site #104
Indianapolis, Indiana, United States
Viking Clinical Site #103
Louisville, Kentucky, United States
Viking Clinical Site #109
Marrero, Louisiana, United States
Viking Clinical Site #102
Kansas City, Missouri, United States
Viking Clinical Site #111
Butte, Montana, United States
Viking Clinical Site #108
Knoxville, Tennessee, United States
Viking Clinical Site #101
Austin, Texas, United States
Viking Clinical Site #118
Austin, Texas, United States
Viking Clinical Site #100
Phoenix, Texas, United States
Viking Clinical Site #115
San Antonio, Texas, United States
Viking Clinical Site #117
San Antonio, Texas, United States
Countries
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Other Identifiers
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VK2735-201
Identifier Type: -
Identifier Source: org_study_id
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