Radiomics-based Models for the Prediction of Pathological Response to Neoadjuvant Therapy in Gastric and Gastroesophageal Cancer

NCT ID: NCT06044961

Last Updated: 2023-09-21

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 80 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2005-01-01
• Study Completion Date: 2022-11-15

Brief Summary

Identifying predictors of response to neoadjuvant therapy in gastric and gastro-oesophageal cancer early in the history of the disease would ensure optimal treatment planning.

The study aims to apply radiomics for the prediction of response to neoadjuvant therapy.

Conditions

Patients With Locally Advanced Carcinoma of the Stomach and Oesophagogastric Junction

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: RETROSPECTIVE

Interventions

CT scan

All pre-operative CT scan collected

Intervention Type: RADIATION

Eligibility Criteria

Inclusion Criteria

• Patients with locally advanced stomach cancer undergoing neoadjuvant chemotherapy and gastrectomy between January 2005 and August 2022

Exclusion Criteria

• Siewert 1 tumors;
• Patients who have received neoadjuvant with the addition of a biological drug;
• Patients who have received radiotherapy;
• Patients without staging CT scan or with insufficient image quality in terms of phases performed, pixel spacing, slide thickness (mandatorily: > 5 mm) or artefacts.

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

Sponsor Role: lead

Responsible Party

Agnes Annamaria

MD

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

5297

Identifier Type: -

Identifier Source: org_study_id