EHR-integrated rUTI Texting Platform

NCT ID: NCT06035601

Last Updated: 2025-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

104 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-07

Study Completion Date

2025-05-31

Brief Summary

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The goal of this clinical trial is to compare a texting platform to usual care for managing recurrent urinary tract infections (UTI).

The main question it aims to answer is:

• can a texting platform that integrates symptom triage and prevention education reduce the rate of unnecessary antibiotics for recurrent UTIs as compared to usual care?

Participants enrolled onto the texting platform will:

• receive evidence-based clinical guidance for the management of symptoms of UTI and receive educational videos on how to prevent UTIs. An important secondary outcome is to determine if the texting platform improves self-efficacy for the management of recurrent UTI.

Detailed Description

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Conditions

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Recurrent Urinary Tract Infection

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Outcome Assessors
Research assistant extracting data on primary and secondary outcomes will be masked to randomization

Study Groups

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Electronic health record (EHR)-integrated texting platform

Patients will be enrolled into a texting platform for the management of recurrent UTI.

Group Type EXPERIMENTAL

EHR-integrated texting platform (Urotrust)

Intervention Type DEVICE

* An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI

Usual care

Patients will receive usual care through their providers.

Group Type ACTIVE_COMPARATOR

Usual care

Intervention Type OTHER

• Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.

Interventions

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EHR-integrated texting platform (Urotrust)

* An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI

Intervention Type DEVICE

Usual care

• Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Provision of signed and dated informed consent form
2. Stated willingness to comply with all study procedures and availability for the duration of the study
3. Females who currently meet the criteria for recurrent UTIs
4. Age 18 years or older
5. Owns a mobile device with text messaging capability
6. Ability to read and write English
7. Currently receiving care from a provider in Penn Urogynecology or Penn Urology

Exclusion Criteria

1. History of known multidrug resistant UTIs
2. History of interstitial cystitis/bladder pain syndrome or current diagnosis of chronic pelvic pain
3. On continuous suppressive antibiotics currently
4. Currently pregnant or within 6 weeks of pregnancy
5. Transplant patient on immunosuppressive medication currently
6. Practice of chronic self-catheterization
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Independence Blue Cross

OTHER

Sponsor Role collaborator

University of Pennsylvania

OTHER

Sponsor Role lead

Responsible Party

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Lily Arya

Professor of OBGYN

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Pennsylvania

Philadelphia, Pennsylvania, United States

Site Status

Countries

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United States

References

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Arya LA, Agrawal S, Ikpeama N, Harvie H, Feldman RH, Dutcher L. Implementing a Digital Platform for Recurrent Urinary Tract Infections. Urogynecology (Phila). 2025 Mar 1;31(3):183-193. doi: 10.1097/SPV.0000000000001604. Epub 2024 Nov 11.

Reference Type DERIVED
PMID: 39527705 (View on PubMed)

Other Identifiers

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853917

Identifier Type: -

Identifier Source: org_study_id

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