Financial Incentives and Recruitment to the APT Webstudy

NCT ID: NCT06033066

Last Updated: 2025-06-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44844 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-01

Study Completion Date

2024-04-30

Brief Summary

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This single-blind, three-arm, randomized, controlled trial will assess the impact of messages and financial incentives on the enrollment of demographically diverse individuals to the Alzheimer Prevention Trials (APT) Webstudy. The APT Webstudy is a novel, online registry that employs quarterly cognitive testing using validated platforms. The APT Webstudy implements fully remote assessments, coordinated by the Alzheimer's Therapeutic Research Institute (ATRI) under USC IRB #HS-17-00746. The purpose of the current study is to test whether we can increase enrollment of diverse individuals into the registry. To do this, we will work with Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers in Contra Costa County, California, to test whether sending messages with and without financial incentives to patients who receive primary care with the health system can increase enrollment to the APT Webstudy. The investigators hypothesize that 1) a certain small financial incentive and an award opportunity based incentive (or a drawing with a prize) will increase enrollment rates of CCHS members into the APT Webstudy relative to the control group. The investigators further hypothesize that the award opportunity incentive will increase the enrollment rate of CCRMC patients into the APT Webstudy more than a certain financial incentive with the same expected value.

Detailed Description

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Conditions

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Alzheimer Disease Dementia Preclinical Alzheimer's Disease Prodromal Alzheimer's Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Messaging Only

16,000 participants will be randomized to Arm 1 where no monetary incentive is offered.

Group Type ACTIVE_COMPARATOR

Message

Intervention Type BEHAVIORAL

Message inviting participant to enroll

Small Incentive

16,000 participants will be randomized to Arm 2 where a small one-time monetary incentive is offered.

Group Type EXPERIMENTAL

Financial Incentives

Intervention Type BEHAVIORAL

Small financial incentive or prize incentive

Prize Incentive

16,000 participants will be randomized to Arm 3 where an opportunity based incentive (or a drawing with a prize) with a single winner will be offered.

Group Type EXPERIMENTAL

Financial Incentives

Intervention Type BEHAVIORAL

Small financial incentive or prize incentive

Interventions

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Financial Incentives

Small financial incentive or prize incentive

Intervention Type BEHAVIORAL

Message

Message inviting participant to enroll

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

To be eligible to participate in this study, an individual must meet all of the following criteria:

* Patients empaneled at Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers.
* Age 50 or older
* Literate in either English or Spanish

Exclusion Criteria

* Below age 50
* Documentation of prior dementia diagnosis
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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American Heart Association

OTHER

Sponsor Role collaborator

Schaeffer Center for Health Policy & Economics

UNKNOWN

Sponsor Role collaborator

Alzheimer's Therapeutic Research Institute

OTHER

Sponsor Role collaborator

University of Southern California

OTHER

Sponsor Role lead

Responsible Party

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Mireille Jacobson

Associate Professor of Gerontology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Contra Costa Health Plan

Martinez, California, United States

Site Status

Countries

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United States

References

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Jacobson M, Molina-Henry D, Chang TY, Jimenez-Maggiora GA, Pramanik R, Shah SB, Aisen PS. Financial Incentives to Increase Diversity of Older Participants in a Memory Concerns Registry: A Randomized Clinical Trial. JAMA Health Forum. 2025 Aug 1;6(8):e252273. doi: 10.1001/jamahealthforum.2025.2273.

Reference Type DERIVED
PMID: 40844772 (View on PubMed)

Provided Documents

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Document Type: Study Protocol

View Document

Related Links

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Other Identifiers

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UP-22-01037

Identifier Type: -

Identifier Source: org_study_id

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