Dual Implant Versus Single Implant Distal End of Femur

NCT ID: NCT06032299

Last Updated: 2025-10-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-04-29

Study Completion Date

2026-02-28

Brief Summary

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This research study is being conducted to examine the effect of two versus one fixation device for fixation of distal femur fractures.

Detailed Description

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Conditions

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Femur Fracture

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Single Distal Femur Implant Group

Subjects will receive one of two types of implants for the distal femur fracture. The single implant will be either a plate and screws or a rod. The type of single implant used will be determined by the surgeon based on the characteristics of the fracture.

Group Type ACTIVE_COMPARATOR

Single Distal Femur Implant

Intervention Type PROCEDURE

Single implant constructs will be either a retrograde intramedullary nail with interlocking screws or a single plate and screw construct.

Dual Distal Femur Implant Group

Subjects will receive two implants for fixation of the distal femur fracture. The dual implant will be either 2 plates with screws or a plate with screws and a rod. The type of dual implant used will be determined by the surgeon based on the characteristics of the fracture.

Group Type EXPERIMENTAL

Dual Distal Femur Implant

Intervention Type PROCEDURE

Dual implant constructs will either be an intramedullary nail with an additional plate and screw construct or dual (two plates in any orientation) plate and screw construct.

Interventions

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Single Distal Femur Implant

Single implant constructs will be either a retrograde intramedullary nail with interlocking screws or a single plate and screw construct.

Intervention Type PROCEDURE

Dual Distal Femur Implant

Dual implant constructs will either be an intramedullary nail with an additional plate and screw construct or dual (two plates in any orientation) plate and screw construct.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Femur fracture distal to the femoral diaphysis.
* Operative treatment within 72 hours of presenting to the treating hospital.
* Patient was previously ambulatory.
* Fracture amendable to either single or dual implant fixation.
* Informed consent can be obtained from the patient, family member, or power of attorney.

Exclusion Criteria

* Associated major lower extremity fracture.
* Ongoing infection.
* History of metabolic bone disease (Paget's, etc).
* Pathologic fracture.
* Open fracture.
* Severe cognitive impairment (Six Item Screener with 3 or more errors).
* Stage 5 Parkinson's disease.
* Significant femoral bone loss requiring planned staged bone grafting.
* Vascular injury.
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Brandon James Yuan

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Brandon Yuan, MD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic Minnesota

Rochester, Minnesota, United States

Site Status

Countries

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United States

Other Identifiers

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22-004415

Identifier Type: -

Identifier Source: org_study_id

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