Effect of Spirulina on Periodontitis

NCT ID: NCT06016933

Last Updated: 2023-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-07-01

Study Completion Date

2023-07-22

Brief Summary

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The purpose of this study is to assess the clinical and immunological effect of spirulina in treatment of stage II periodontitis.

Detailed Description

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In this study, the investigators tested the effect of spirulina gel as adjunctive of scaling and root planing in treatment of stage II, grade B periodontitis in term of probing pocket depth reduction, mean gain in clinical attachment level, and level of interleukin 6.

Conditions

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Periodontitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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oral hygiene instructions and SRP of all teeth plus placebo gel.

Group Type PLACEBO_COMPARATOR

SRP of all teeth

Intervention Type PROCEDURE

Patients received oral hygiene instructions and SRP of all teeth.

oral hygiene instructions and SRP of all teeth, followed by insertion of the spirulina gel.

Group Type ACTIVE_COMPARATOR

spirulina gel

Intervention Type DRUG

Patient were received spirulina gel in diseased sites. The process will be repeated at 7, 14, 21 days.

SRP of all teeth

Intervention Type PROCEDURE

Patients received oral hygiene instructions and SRP of all teeth.

Interventions

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spirulina gel

Patient were received spirulina gel in diseased sites. The process will be repeated at 7, 14, 21 days.

Intervention Type DRUG

SRP of all teeth

Patients received oral hygiene instructions and SRP of all teeth.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All the patients suffer from stage II, grade B periodonitis with attachment loss 3-4 mm and probing pocket depth ≤ 5mm.

Exclusion Criteria

* Any systemic disease that affects the periodontium. ·
* Pregnant, postmenopausal women. ·
* People who take anti-inflammatory drugs, antibiotics, or vitamins within the previous 3 month.
* People who use mouth washes regularly ·
* Participation in other clinical trials.
Minimum Eligible Age

35 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kafrelsheikh University

OTHER

Sponsor Role lead

Responsible Party

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Enas Elgendy

Prof. of Oral Medicine and Periodontology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Kafrelsheikh University

Tanta, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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5

Identifier Type: -

Identifier Source: org_study_id

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