Life-2023-02 Esophagogastric Variceal Bleeding

NCT ID: NCT06011980

Last Updated: 2023-08-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

33 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-08-31

Study Completion Date

2026-08-10

Brief Summary

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Study on the efficacy of the growth inhibitors after endoscopic treatment of acute esophagogastric variceal bleeding

Detailed Description

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Participants with acute esophagogastric variceal bleeding in 5 days and under stable status will be included in this study. All the patients will take CTP test to confirm the blood flow status of the portal vein before endoscopic treatment. After that they will be randomly divided into two groups: A. accept growth inhibitors after the endoscopic treatment for 5 days; B. no growth inhibitor will be applied after the treatment.

Conditions

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Acute Esophageal Variceal Hemorrhage

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Group A

Participants in this group will take growth inhibitors for 5 days after endoscopic treatment.

Group Type EXPERIMENTAL

Growth Inhibitor

Intervention Type DRUG

growth inhibitors for 250-500μg/h, ivgtt. for 5 days

Group B

Participants in this group will not take growth inhibitor treatment after endoscopic treatment.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Growth Inhibitor

growth inhibitors for 250-500μg/h, ivgtt. for 5 days

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* acute esophagogastric bleeding with hepatic cirhosis;
* stable status (no active bleeding)

Exclusion Criteria

* endoscopic test limitation;
* previous acute esophagogastric bleeding treatment history;
* ICU;
* pregnant;
* Immunity disabled;
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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2nd Affiliated Hospital, School of Medicine, Zhejiang University

Hanzhou, Zhejiang, China

Site Status RECRUITING

Countries

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China

Central Contacts

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WEI WEI

Role: CONTACT

15267175186

Facility Contacts

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WEI WEI

Role: primary

Other Identifiers

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2023-0407

Identifier Type: -

Identifier Source: org_study_id

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