A 6-month Follow-up Study of Patients With Severe Fever With Thrombocytopenia Syndrome

NCT ID: NCT06011902

Last Updated: 2023-08-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-25

Study Completion Date

2024-03-31

Brief Summary

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This is a multi-center, retrospective clinical study to analyze the clinical features, laboratory indicators, imaging changes, treatment options and long-term prognosis in patients with sever fever with thrombocytopenia syndrome. All hospitalized patients with sever fever with thrombocytopenia diagnosed between 2016 and 2022 were included from the electronic medical record system of 8 centers, and demographics, hospitalization information, clinical information, laboratory or imaging examinations, treatment options, and outcomes were collected.

Detailed Description

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Conditions

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Severe Fever With Thrombocytopenia Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age and gender are not limited;
* Hospitalized patients diagnosed with severe fever with thrombocytopenia syndrome have at least one of the following laboratory test results: serum severe fever with thrombocytopenia syndrome bunyavirus (SFTSV)-specific IgM antibody positive or IgG antibody level increased more than 4 times; or positive for SFTSV RNA; or positive for SFTSV nucleic acid detected by real-time fluorescent quantitative RT-PCR; or SFTSV isolated from case specimens.

Exclusion Criteria

* Patients who were found to be positive for other tick-borne pathogens by PCR analysis of blood samples in the acute phase;
* It is difficult to conduct outpatient follow-up due to mental disorders, dementia, combined diseases such as osteoarthropathy, stroke, pulmonary embolism, etc. that lead to inability to move freely;
* No outpatient follow-up visit after discharge, and repeated confirmation by phone call still unable to get in touch;
* Due to living in other places, nursing homes, welfare homes, unable to participate in outpatient follow-up after making an appointment by phone;
* Currently participating in clinical trials of other drugs or medical devices;
* The researchers think it is not suitable for inclusion.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tongji Hospital

OTHER

Sponsor Role lead

Responsible Party

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Qin Ning

Director and Chair of Department of Infectious Diseases

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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NO.1 Peoples Hospital of Guangshui

Guangshui, Hubei, China

Site Status RECRUITING

Huanggang Central Hospital

Huanggang, Hubei, China

Site Status RECRUITING

People's Hospital Of Luotian County

Huanggang, Hubei, China

Site Status RECRUITING

People's Hospital of Macheng city Affiliated Hospital of Hubei Univerciy of science and technology

Macheng, Hubei, China

Site Status RECRUITING

Suizhou Central Hospital

Suizhou, Hubei, China

Site Status RECRUITING

Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

Wuhan, Hubei, China

Site Status RECRUITING

Xianning Central Hospital

Xianning, Hubei, China

Site Status RECRUITING

Yichang Third Peoples Hospital

Yichang, Hubei, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Qin Ning, Professor

Role: CONTACT

+8613971521450

Facility Contacts

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qian Liu

Role: primary

yaping Li

Role: primary

wei Wang

Role: primary

yi Zhou

Role: primary

tiantong Zhou

Role: primary

Qin Ning, professor

Role: primary

jun Zhu

Role: primary

quan Ming

Role: primary

Other Identifiers

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RESORT

Identifier Type: -

Identifier Source: org_study_id

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