Evaluation of Patient-Reported Outcomes Measurement Information System (PROMIS)-29 v2.1 for Postpartum Women

NCT ID: NCT06002763

Last Updated: 2025-07-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-09

Study Completion Date

2026-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

There is no widely used, statistically validated assessment for physical and mental health for the short- to medium-term in a postpartum population. PROMIS-29 has been validated for the assessment of these factors in a generic population, but has not been specifically evaluated for use with postpartum women.

This study is a longitudinal, single center observational cohort study designed to evaluate the reliability of the Patient-Reported Outcomes Measurement Information System (PROMIS)-29 v2.1 survey in a postpartum population. PROMIS-29 is a survey designed to screen for pain, impairments in mood, physical function, and activities of daily living. While this survey has shown utility in other populations, it has yet to be assessed in an obstetric population. The investigators plan to recruit patients who are recently postpartum from vaginal or cesarean delivery to complete virtual surveys at defined time points (0, 2, 6, and 12 weeks after delivery). The investigators will subject survey data to statistical measures of validity and reliability comparing with contemporaneously collected surveys of established metrics for quality of life (WHOQoLBREF) and general (global) state of health (numerical rating score 1-100).

The hypothesis is that the PROMIS-29 v2.1 questionnaire is a statistically valid and reliable means of assessing physical and mental health in a postpartum population.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Well-Being, Psychological

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Vaginal delivery

Patients who have vaginal deliveries with neuraxial labour analgesia.

PROMIS-29 v2.1 (Patient-Reported Outcomes Measurement Information System)

Intervention Type OTHER

PROMIS-29 is a survey designed to screen for pain, impairments in mood, physical function, and activities of daily living.

WHOQoLBREF (World Health Organization Quality of Life Brief Version)

Intervention Type OTHER

The WHOQOL-BREF is a 26-item version of the 100-item WHOQOL-100 quality of life measure that addresses four quality of life domains: physical health, psychological health, social relationships and environment.

EQ-5D-3L1 (not an acronym)

Intervention Type OTHER

The EQ-5D-3L1 is a generic measure of health status consisting of two parts. The first part assesses health in five dimensions: MOBILITY, SELFCARE, USUAL ACTIVITIES, PAIN / DISCOMFORT, ANXIETY/DEPRESSION. The second part of the questionnaire consists of a VAS on which the patient rates their perceived health from 0 (the worst imaginable health) to 100 (the best imaginable health).

Cesarean delivery

Patients who have a scheduled cesarean delivery with neuraxial anesthesia.

PROMIS-29 v2.1 (Patient-Reported Outcomes Measurement Information System)

Intervention Type OTHER

PROMIS-29 is a survey designed to screen for pain, impairments in mood, physical function, and activities of daily living.

WHOQoLBREF (World Health Organization Quality of Life Brief Version)

Intervention Type OTHER

The WHOQOL-BREF is a 26-item version of the 100-item WHOQOL-100 quality of life measure that addresses four quality of life domains: physical health, psychological health, social relationships and environment.

EQ-5D-3L1 (not an acronym)

Intervention Type OTHER

The EQ-5D-3L1 is a generic measure of health status consisting of two parts. The first part assesses health in five dimensions: MOBILITY, SELFCARE, USUAL ACTIVITIES, PAIN / DISCOMFORT, ANXIETY/DEPRESSION. The second part of the questionnaire consists of a VAS on which the patient rates their perceived health from 0 (the worst imaginable health) to 100 (the best imaginable health).

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

PROMIS-29 v2.1 (Patient-Reported Outcomes Measurement Information System)

PROMIS-29 is a survey designed to screen for pain, impairments in mood, physical function, and activities of daily living.

Intervention Type OTHER

WHOQoLBREF (World Health Organization Quality of Life Brief Version)

The WHOQOL-BREF is a 26-item version of the 100-item WHOQOL-100 quality of life measure that addresses four quality of life domains: physical health, psychological health, social relationships and environment.

Intervention Type OTHER

EQ-5D-3L1 (not an acronym)

The EQ-5D-3L1 is a generic measure of health status consisting of two parts. The first part assesses health in five dimensions: MOBILITY, SELFCARE, USUAL ACTIVITIES, PAIN / DISCOMFORT, ANXIETY/DEPRESSION. The second part of the questionnaire consists of a VAS on which the patient rates their perceived health from 0 (the worst imaginable health) to 100 (the best imaginable health).

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Patient-Reported Outcomes Measurement Information System World Health Organization Quality of Life Brief Version Global state of health numerical rating score 1-100

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18 years old and over
* singleton births
* 37 or more weeks gestational age
* multiparous or nulliparous patients
* spontaneous vaginal delivery or scheduled cesarean delivery with labor analgesia or neuraxial anesthesia
* give informed written consent

Exclusion Criteria

* refusal to take part
* are unable to give or have withdrawn consent
* patients unable to communicate fluently in English
* patients who are less than 18 years old
* patients who had fetal demise or severely morbid fetal conditions such as intubation, cooling, expected surgical correction of congenital anomaly during hospitalization (although NICU admissions will be included)
* patients who were admitted in ICU
* patients who had failed neuraxial analgesia such as replaced epidurals or failed spinal requiring conversion to general anesthesia
* patients who had general anesthesia for cesarean delivery as defined by "GETA", including sedatives and deep sedation if not intubated
* patients who had intrapartum cesarean or had assisted/operative (i.e. vacuum, forceps) vaginal delivery.
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Ronald George, MD

Role: PRINCIPAL_INVESTIGATOR

MOUNT SINAI HOSPITAL

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Mount Sinai Hospital

Toronto, Ontario, Canada

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Canada

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Ronald George, MD

Role: CONTACT

416-586-4800 ext. 2681

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Ronald George, MD

Role: primary

416-586-4800 ext. 2681

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

23-03

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Maternal Mental Health Access - MaMa
NCT06049433 RECRUITING NA
Postpartum Weight Retention
NCT02867631 COMPLETED NA