Real-World Study of Iruplinalkib in the Treatment of ALK-Positive Non-Small Cell Lung Cancer

NCT ID: NCT05991895

Last Updated: 2023-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-07-24

Study Completion Date

2026-07-31

Brief Summary

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This study is a national multicenter real-world investigation aimed at evaluating the real-world effectiveness and safety of Iruplinalkib in the treatment of ALK-positive NSCLC in China.

The study aims to enroll ALK-positive NSCLC patients who have undergone treatment with Iruplinalkib prior to enrollment. Demographic information, medical history, Iruplinalkib-containing treatment regimens, clinical outcomes, adverse events, and related data will be collected for all enrolled patients.

As this study is a real-world investigation, treatment procedures, visit schedules, and examinations will be based on the routine clinical practice of physicians. The primary sources of data for this study will mainly consist of patients' routine medical records or healthcare documentation.

Detailed Description

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Conditions

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Non-small Cell Lung Cancer (NSCLC)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Iruplinalkib

Iruplinalkib is administered orally with approximately fixed dosing times each day. The recommended dosage is once daily, on an empty stomach or with food, at 60 mg per dose for the first 1 to 7 days. If tolerated, the dosage is increased to 180 mg per dose starting from the 8th day.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients willingly contribute their clinical data for this study
* Patients with ALK-positive non-small cell lung cancer
* Age ≥ 18 years
* Patients who have undergone treatment with Iruplinalkib.

Exclusion Criteria

* Known pregnant or lactating females
* Patients with interstitial lung diseases, drug-related pneumonitis, or radiation pneumonitis require ongoing medical intervention.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Jinming Yu

OTHER

Sponsor Role lead

Responsible Party

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Jinming Yu

Director of the hospital

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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JinMing Yu, PhD

Role: PRINCIPAL_INVESTIGATOR

Shandong Cancer Hospital and Institute

Locations

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Shandong Cancer Hospital and Institute

Jinan, Shandong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Jinming Yu, PhD

Role: CONTACT

8613806406293

Linlin Wang, PhD

Role: CONTACT

8613793187739

Facility Contacts

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Linlin Wang

Role: primary

+8613793187739

Other Identifiers

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IRU-RWS-001

Identifier Type: -

Identifier Source: org_study_id

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