Intraperitoneal Dexamethasone, Dexmedetomidine, and Dexamethasone-Dexmedetomidine Combination on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
NCT ID: NCT05988671
Last Updated: 2025-06-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
120 participants
INTERVENTIONAL
2023-08-10
2024-08-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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Control group
received 20 ml normal saline
normal Saline
Intraperitoneal route
dexamethasone group
received 8mg dexamethasone
Dexamethasone
Intraperitoneal route
dexmedetomidine group
received dexmedetomidine 1mic/kg
Dexmedetomidine
Intraperitoneal route
combined group
received combination of both 8mg dexamethasone+ dexmedetomidine 1mic/kg
Combination of dexamethasone + dexmedetomidine
Intraperitoneal route
Interventions
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normal Saline
Intraperitoneal route
Dexamethasone
Intraperitoneal route
Dexmedetomidine
Intraperitoneal route
Combination of dexamethasone + dexmedetomidine
Intraperitoneal route
Eligibility Criteria
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Inclusion Criteria
* ASA I OR II
* undergo laparoscopic cholecystectomy
Exclusion Criteria
* Parkinson's disease
* motion disorder
* Smoker
* or history of chemotherapy
20 Years
50 Years
ALL
No
Sponsors
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Benha University
OTHER
Al-Azhar University
OTHER
Responsible Party
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Neveen Abd El Maksoad Kohaf
Lecturer of Clinical Pharmacy
Locations
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Haney Baumey
Banhā, , Egypt
Neveen Kohaf
Tanta, , Egypt
Countries
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References
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Bauiomy H, Kohaf NA, Saad M, Rashed ZF, Abosakaya AM. Study the Effect of Intraperitoneal Dexamethasone, Dexmedetomidine, and Their Combination on PONV After Laparoscopic Cholecystectomy: A Randomized Triple-Blind Trial. Anesthesiol Res Pract. 2025 Feb 24;2025:4976637. doi: 10.1155/anrp/4976637. eCollection 2025.
Other Identifiers
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RC 10-3-2023
Identifier Type: -
Identifier Source: org_study_id
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