Post Market Clinical Follow-Up Study - Medical Device KalobaGOLA ( PMCF )

NCT ID: NCT05985837

Last Updated: 2024-04-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-08-02

Study Completion Date

2023-10-31

Brief Summary

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The goal of this observational PMCF study is to confirm the efficacy and safety of the medical device KalobaGola (oral spray and tablets) in children, adolescents and adults with sore throat and /or pharyngitis. The main questions it aims to answer are:

* Is the product effective in the treatment of sore throat / pharyingits?
* Is the product safe?

After buying the product, participants will be asked to fill in a questionnaire, in order to:

1. Assess the sore throat symptoms before the use of the spray or tablets.
2. Assess the resolution of sore throat / pharyngitis symptoms after the use of the spray or tablets.
3. Describe the adverse effect(s)/problem(s) observed while using the product (if any).

Detailed Description

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The Medical Device Regulation (EU) 2017/745 (MDR) considers post-market clinical follow-up (PMCF) as a continuous process that aims to update the clinical evaluation and validate or reassess the benefit-risk balance of the medical device. The PMCF is an integral part of the manufacturer's post-market surveillance plan (PMS).

The medical devices in question are both CE marked since 2020, with no substantial modification.

The objectives of this Post Market Clinical Follow Up (PMCF) study are: verify the use of these devices in a real situation, verify if their efficacy and safety of use are aligned with the provisions of the clinical evaluation; confirm or reassess the benefit/risk balance; update the risk analysis; identify any need for CAPA.

Specific product questionnaires have been developed based on the validated STAT-10 questionnaire, which aim to investigate aspects of Real-World Evidence on efficacy, safety, even in specific categories or situations, known and unknown adverse events, difficulties in use or completeness and clarity of IFUs.

Given the low-risk class of the devices (class IIa - Dir. 93/42/EEC), which are intended for use by lay people and normally sold in pharmacies / parapharmacies, the sponsor planned to distribute the questionnaires to users that have purchased the product through health professionals (pharmacists), who are normally in charge of the distribution of the products.

The questionnaire was prepared in simple and easily understandable language for lay people.

The data requested during the filling of the questionnaire does not provide for the collection of information that allows the sponsor an identification of the participant.

Data will be collected and processed in a totally anonymous form.

Conditions

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Sore-throat Pharyngitis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Adolescents and adults

Adolescents from 12 years old and adults with sore throat and/or pharyngitis, who have bought the product.

KalobaGOLA spray (1)

Intervention Type DEVICE

Oral spray, 2-4 spray, till 8 times per day

KalobaGOLA tablets

Intervention Type DEVICE

1 tablets, 6 times per day

Children 1-6 years

Children from 1 to 6 years old with sore throat and/or pharyngitis, whose parents/caregivers have bought the product.

KalobaGOLA spray (2)

Intervention Type DEVICE

Oral spray, 2-4 spray, till 4 times per day

Children 6-12 years

Children from 6 to 12 years old with sore throat and/or pharyngitis, whose parents/caregivers have bought the product.

KalobaGOLA spray (1)

Intervention Type DEVICE

Oral spray, 2-4 spray, till 8 times per day

KalobaGOLA tablets

Intervention Type DEVICE

1 tablets, 6 times per day

Interventions

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KalobaGOLA spray (1)

Oral spray, 2-4 spray, till 8 times per day

Intervention Type DEVICE

KalobaGOLA spray (2)

Oral spray, 2-4 spray, till 4 times per day

Intervention Type DEVICE

KalobaGOLA tablets

1 tablets, 6 times per day

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* KalobaGOLA spray: children from 1 year, adolescents and adults, both sexes, with symptoms of sore throat (burning sensation, pharyngitis, pain on swallowing), who / whose parents or caregivers bought the product by the pharmacy/parapharmacy involved.
* KalobaGOLA tablets: children from 6 years, adolescents and adults, both sexes, with symptoms of sore throat (burning sensation, pharyngitis, pain on swallowing), who / whose parents or caregivers bought the product by the pharmacy/parapharmacy involved.

Exclusion Criteria

* KalobaGOLA spray: children aged \< 1 year, people without sore throat symptoms
* KalobaGOLA tablets: children aged \< 6 years, people without sore throat symptoms
Minimum Eligible Age

1 Year

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Schwabe Pharma Italia

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Schwabe Pharma Italia

Neumarkt, Bolzano, Italy

Site Status

Countries

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Italy

Other Identifiers

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KG-01-2023

Identifier Type: -

Identifier Source: org_study_id

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