Reoperation Rate in Breast-Conserving Surgery Using Confocal Histolog® Scanner for Intraoperative Margin Assessment

NCT ID: NCT05946759

Last Updated: 2024-03-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-10

Study Completion Date

2024-03-12

Brief Summary

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This PMPF study is proposed to evaluate in real life the reoperation rates (ROR) of breast cancer and/or DCIS surgery when including the use of the HLS in the context of breast lumpectomy margin assessment.

Detailed Description

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Conditions

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Breast Cancer - Ductal Carcinoma in Situ (DCIS) Breast-Conserving Surgery

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Prospective

50 prospective subjects

Group Type ACTIVE_COMPARATOR

Histolog Scanner

Intervention Type DEVICE

The PMPF study is collecting data that includes the use of the CE Mark IVD Histolog Scanner for the breast lumpectomy margin assessment.

Historical

40 historical subjects

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Histolog Scanner

The PMPF study is collecting data that includes the use of the CE Mark IVD Histolog Scanner for the breast lumpectomy margin assessment.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult female Subject ≥18 years old.
* Subject Scheduled for breast conserving surgery of invasive and/or in-situ ductal carcinoma.
* Subject is able to read, understand and sign the informed consent.

Exclusion Criteria

* Subject previously treated for ipsilateral breast cancer and/or ductal carcinoma in situ surgery.
* Subject with previous radiotherapy of the ipsilateral breast.
* Subject with multicentric/multilateral breast cancer.
* Subject with planned mastectomy, tumor-adapted breast reduction.
* Subject with pre-surgical/ preoperative neo-adjuvant treatment.
* Subject is pregnant/ lactating.
* Participation in any other clinical study that would affect data acquisition.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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St. Vincenz Krankenhaus GmbH, Paderborn

UNKNOWN

Sponsor Role collaborator

SamanTree Medical SA

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michael P Lux, Prof. Dr MBA

Role: PRINCIPAL_INVESTIGATOR

St. Vincenz Krankenhaus GmbH, Paderborn

Locations

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St. Vincenz-Krankenhaus GmbH, Frauenklinik St. Louise

Paderborn, , Germany

Site Status

Countries

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Germany

Other Identifiers

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SHIELD

Identifier Type: -

Identifier Source: org_study_id

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