Investigation of the Effects of Motor Cognitive Dual Task Exercises on Cognitive Function, Balance and Functional Capacity in Patients Who Have Undergone Liver Transplantation.

NCT ID: NCT05909371

Last Updated: 2026-01-15

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 32 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-02-01
• Study Completion Date: 2024-01-01

Brief Summary

Liver transplantation is a life-saving treatment of choice for patients with acute or chronic liver failure. Liver transplantation is performed with a graft taken from a living donor or cadaver in patients with end-stage liver failure or who develop various complications regardless of the stage of the disease.In liver diseases, cognitive problems occur as well as physical problems. It has been observed that in some liver diseases, including hepatitis C, Wilson's disease, primary biliary cirrhosis, cognitive dysfunction that negatively affects the quality of life of patients, from mild cognitive problems to hepatic encephalopathy.

Our study will be carried out in Malatya İnönü University Turgut Özal Medical Center Liver Transplant Institute Hospital in order to investigate the effects of motor-cognitive dual-task exercises on cognitive function, balance and functional capacity in liver transplant patients.It will be divided into 2 groups as classical physiotherapy and motor-cognitive exercise. Classical physiotherapy and motor-cognitive exercise programs will be applied to the groups in accordance with the clinical characteristics of the individuals, tolerable, and in a standardized manner specific to the individuals. Evaluations will be made on the first day and at the end of the twenty-fourth session while the patient is in the service before starting the treatment.

Conditions

Liver Transplantation

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: TRIPLE

Study Groups

Classical physiotheraphy

The Program Applied to the Classical Physiotherapy Group The Warm-Up The postural exercises Short Breathing exercises Strengthening exercises Don't sit up Daily Balance exercises Walking exercises Pre-cooling exercise An individual-specific standardized exercise program suitable for clinical characteristics will be applied to patients with a maximum of 1 set of 8-12 repetitions for 30-45 minutes for each exercise (Modified Borg scale 4-6).

Group Type: EXPERIMENTAL

exercise

Intervention Type: OTHER

Application of two different exercises to liver transplant individuals.

Motor cognitive exercise group

The Program to be Applied in addition to the Physiotherapy Program to the Motor-cognitive Exercise Group .Remembering the word. Color/week/month/animal names counting/// girls boy names counting/// Country City names counting.

from 50 back to 2 bad, 3 er,// counting from 50 back to 4 er//counting from 100 back to 2 bad 2 bad 3 er 3 er and simple arithmetic problems with single digits.

Counting the months of the year// Counting the months of the year starting from any month// Counting the months of the year and 30 31 days.

Group Type: EXPERIMENTAL

exercise

Intervention Type: OTHER

Application of two different exercises to liver transplant individuals.

Interventions

exercise

Application of two different exercises to liver transplant individuals.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Be able to mobilize alone
• Having performed a liver transplant over the age of 50
• Spontaneous breathing
• Being hemodynamically stable
• Ability to read and write
• Not having an orthopedic disability and functional capacity limitation
• Being conscious and cooperative

Exclusion Criteria

• Not agreeing to participate in the study
• Not continuing the treatment regularly
• Having neurological or neuropsychiatric problems
• Being colorblind

• Minimum Eligible Age: 50 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Hasan Kalyoncu University

OTHER

Sponsor Role: lead

Responsible Party

İlker DEMİR

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Hasan Kalyoncu University

Gaziantep, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

Hasankalyoncüüniversityilker

Identifier Type: -

Identifier Source: org_study_id