Correlation of Biochemical Indexes and Retinal Hemodynamic in Patients With Different Degrees of Diabetic Retinopathy

NCT ID: NCT05902650

Last Updated: 2023-06-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2023-12-31

Brief Summary

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All OCTA data and biochemical indexes of diabetic patients were acquired. A prediction model of diabetic retinopathy was built, and the random forest method was used to identify sensitive indicators.

Detailed Description

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Diabetic patients at the Department of Ophthalmology of the Seventh Affiliated Hospital of Sun Yat-sen University were selected as research participants. All OCTA data and biochemical indexes were acquired. A prediction model of diabetic retinopathy was built, and the random forest method was used to identify sensitive indicators.

Conditions

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Diabetic Retinopathy

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Group 1

diabetic patients with no diabetic retinopathy

imaging

Intervention Type DIAGNOSTIC_TEST

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Group 2

diabetic patients with mild nonproliferative diabetic retinopathy

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Intervention Type DIAGNOSTIC_TEST

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Group 3

diabetic patients with moderate and severe nonproliferative diabetic retinopathy

imaging

Intervention Type DIAGNOSTIC_TEST

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Group 4

diabetic patients with proliferative diabetic retinopathy

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Intervention Type DIAGNOSTIC_TEST

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Interventions

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imaging

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Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of diabetes

Exclusion Criteria

* various other types of retinal and choroidal disease;
* history of any intraocular surgery or treatment (including intravitreal injection, retinal photocoagulation etc.
* with severe refractive medium opacity that could affect fundus examination.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mingzhe Cao

OTHER

Sponsor Role lead

Responsible Party

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Mingzhe Cao

Attending ophthalmologist

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Mingzhe Cao

Role: PRINCIPAL_INVESTIGATOR

The Seventh Affiliated Hospital of Sun Yat-sen University

Locations

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The Seventh Affiliated Hospital, Sun Yat-sen University

Shenzhen, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Mingzhe Cao, Dr.

Role: CONTACT

13060822790

Facility Contacts

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Kuiqing Lu

Role: primary

075581207047

Other Identifiers

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MCao

Identifier Type: -

Identifier Source: org_study_id

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