A Causal Relationship Study Between Anxiety, Depression, and Rheumatoid Arthritis

NCT ID: NCT05892562

Last Updated: 2023-06-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-15

Study Completion Date

2023-07-15

Brief Summary

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Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease, and depression and anxiety are among the most common comorbidities in RA patients, with a high prevalence rate. Epidemiological studies have found that joint deformities, severe pain, positive serum RF titers, as well as comorbidities such as hypertension, insomnia, pain, and fatigue are significantly associated with depression and anxiety in RA patients.

Currently, clinical studies have found that the relief of depression or anxiety is one of the expected treatment goals for RA patients. Due to the unclear pathogenic factors of depression or anxiety in RA patients, there is a lack of effective clinical treatment options. Therefore, this study will use a "causal inference model" to identify possible "mediating variables" that may lead to the comorbidity of RA and emotional disorders through clinical investigation, aiming to improve the precision of treatment for physicians.

Detailed Description

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Conditions

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Rheumatoid Arthritis Anxiety Depression

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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RA combined with depression or anxiety

No intervention

Intervention Type OTHER

As this study is purely observational, no intervention is involved.

RA without comorbid depression or anxiety

No intervention

Intervention Type OTHER

As this study is purely observational, no intervention is involved.

Interventions

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No intervention

As this study is purely observational, no intervention is involved.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed with RA.

Exclusion Criteria

* Patients diagnosed as non-RA.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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First Affiliated Hospital of Zhejiang University

OTHER

Sponsor Role collaborator

Shate Xiang

OTHER_GOV

Sponsor Role lead

Responsible Party

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Shate Xiang

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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The Second Affiliated Hospital of Zhejiang Chinese Medical University

Hangzhou, None Selected, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Shate Xiang, Master's degree

Role: CONTACT

15157147753

Facility Contacts

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Shate Xiang

Role: primary

+8615157147753

Other Identifiers

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Shate Xiang

Identifier Type: -

Identifier Source: org_study_id

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