Development and Validation of a Risk Prediction Model for Preoperative Frailty in Elderly Patients With Colorectal Cancer

NCT ID: NCT05879861

Last Updated: 2023-05-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

364 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-08-01

Study Completion Date

2025-07-31

Brief Summary

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Fried Scale and its related scales were used to analyze the status and risk factors of preoperative frailty in elderly patients with colorectal cancer. R software was used to construct a risk prediction model for preoperative frailty in elderly patients with colorectal cancer, and its validity and stability were verified in clinical practice.

Detailed Description

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Conditions

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Colorectal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. patients who met the diagnostic criteria of colorectal cancer in Chinese Guidelines for Diagnosis and Treatment of Colorectal Cancer 2020 Edition and underwent surgery;
2. patients aged ≥60 years old ;
3. patients who are clearly conscious, able to understand instructions, communicate normally, and complete the physical activity ability test without the assistance of others;
4. patients who gave informed consent and volunteered to participate in the study.

Exclusion Criteria

1. patients with limb joint disease and lower limb pain;
2. patients with serious heart, liver, kidney diseases could not complete the test;
3. patients with visual impairment and hearing impairment;
4. patients with a history of mental illness or drug dependence;
5. taking antidepressants, levodopa/carbidopa, donepezil hydrochloride and other drugs ;
6. patients who received preoperative radiotherapy and chemotherapy;
7. Patients with hypothyroidism, Parkinson's disease, stroke and other diseases.
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zunyi Medical College

OTHER

Sponsor Role lead

Responsible Party

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Yongmei Zhang

Study Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yongmei Zhang

Role: STUDY_DIRECTOR

Zunyi Medical College

Locations

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Yongmei Zhang

Zunyi, Guizhou, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yongmei Zhang

Role: CONTACT

13885257269

Facility Contacts

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Yongmei Zhang

Role: primary

13885257269

Other Identifiers

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ZSKHZ Zi (2022) no. 337

Identifier Type: -

Identifier Source: org_study_id

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