Methylene Blue Mouthwash for the Treatment of Oral Mucositis Pain in Patients With Cancer
NCT ID: NCT05878405
Last Updated: 2025-04-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
49 participants
INTERVENTIONAL
2023-06-06
2024-12-06
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
NONE
Study Groups
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Standard of Care Mouthwash Group
Patients receive standard of care mouthwash as needed on study.
Anti-inflammatory/Antimicrobial/Analgesic Aqueous Mouth Rinse
Given PO
Methylene Blue Mouthwash Group
Patients receive Methylene Blue mouthwash as needed on study.
Methylene Blue Oral Rinse
Given PO
Interventions
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Anti-inflammatory/Antimicrobial/Analgesic Aqueous Mouth Rinse
Given PO
Methylene Blue Oral Rinse
Given PO
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Admitted to the inpatient setting
* Pain related to oral mucositis
* Experiencing oropharyngeal pain
* Able to provide informed consent
Exclusion Criteria
* Pregnant or nursing women
* Any contraindication to methylene blue including severe hypersensitivity to methylene blue and patients with glucose-6-phosphate dehydrogenase deficiency (G6PD) due to the risk of hemolytic anemia
18 Years
ALL
No
Sponsors
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Mayo Clinic
OTHER
Responsible Party
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Principal Investigators
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Regina M Mackey, M.D.
Role: PRINCIPAL_INVESTIGATOR
Mayo Clinic in Rochester
Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, United States
Countries
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Related Links
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Mayo Clinic Clinical Trials
Other Identifiers
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NCI-2023-03542
Identifier Type: REGISTRY
Identifier Source: secondary_id
22-007588
Identifier Type: OTHER
Identifier Source: secondary_id
22-007588
Identifier Type: -
Identifier Source: org_study_id
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