Characterization of Natural IL-6 Inhibition in Healthy Individuals
NCT ID: NCT05867524
Last Updated: 2023-05-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
40 participants
INTERVENTIONAL
2022-11-01
2024-02-01
Brief Summary
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The study is the first to investigate individuals with extreme amounts of c-aAb levels against IL-6 and to contribute with knowledge on a possible new phenotype.
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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High IL-6 c-aAb
Individuals with top percentile IL-6 c-aAb
Oral Glucose Tolerance Test
75g oral glucose tolerance test, sampled over three hours
Cycling test
2 hours of moderate activity level cycling
Low IL-6 c-aAb
Individually matched controls with low IL-6 c-aAb
Oral Glucose Tolerance Test
75g oral glucose tolerance test, sampled over three hours
Cycling test
2 hours of moderate activity level cycling
Interventions
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Oral Glucose Tolerance Test
75g oral glucose tolerance test, sampled over three hours
Cycling test
2 hours of moderate activity level cycling
Eligibility Criteria
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Inclusion Criteria
* Have extreme amounts of IL-6 c-aAb or matched as control (low amounts of IL-6 c-aAb)
Exclusion Criteria
ALL
Yes
Sponsors
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Clinical Immunological Department, Rigshospitalet
UNKNOWN
The Danish Blood Donor Study
UNKNOWN
University of Copenhagen
OTHER
Responsible Party
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Torben Hansen
Professor
Principal Investigators
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Torben Hansen, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Copenhagen
Locations
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Frederiksberg Hospital
Frederiksberg, , Denmark
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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H-20082776
Identifier Type: -
Identifier Source: org_study_id
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