Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light
NCT ID: NCT05865431
Last Updated: 2025-04-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
17 participants
INTERVENTIONAL
2017-03-17
2018-02-02
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
PREVENTION
NONE
Study Groups
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Zinc Oxide, Avobenzone, No Product
Participants have zinc oxide, avobenzone, and no product applied to 3 different spots on the forearm and singlet oxygen is measured after UV exposure.
Zinc Oxide and Avobenzone
Zinc Oxide is applied to one area of the forearm, Avobenzone is applied to another area of the forearm.
Interventions
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Zinc Oxide and Avobenzone
Zinc Oxide is applied to one area of the forearm, Avobenzone is applied to another area of the forearm.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Aspirin use
* Multivitamins and supplements that contain vitamin E
* Adults unable to consent
* Individuals who are not yet adults (infants, children, teenagers)
* Pregnant women
* Prisoners
18 Years
ALL
Yes
Sponsors
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University of California, Davis
OTHER
Responsible Party
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Locations
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University of California, Davis
Sacramento, California, United States
Countries
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References
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Tewari A, Grage MM, Harrison GI, Sarkany R, Young AR. UVA1 is skin deep: molecular and clinical implications. Photochem Photobiol Sci. 2013 Jan;12(1):95-103. doi: 10.1039/c2pp25323b.
Langstaff SR. Nursing care study. Rheumatoid arthritis treated with penicillamine. Nurs Times. 1975 Jun 12;71(24):918-9. No abstract available.
Menter JM, Hatch KL. Clothing as solar radiation protection. Curr Probl Dermatol. 2003;31:50-63. doi: 10.1159/000072237.
Wang F, Smith NR, Tran BA, Kang S, Voorhees JJ, Fisher GJ. Dermal damage promoted by repeated low-level UV-A1 exposure despite tanning response in human skin. JAMA Dermatol. 2014 Apr;150(4):401-6. doi: 10.1001/jamadermatol.2013.8417.
Sklar LR, Almutawa F, Lim HW, Hamzavi I. Effects of ultraviolet radiation, visible light, and infrared radiation on erythema and pigmentation: a review. Photochem Photobiol Sci. 2013 Jan;12(1):54-64. doi: 10.1039/c2pp25152c.
Hanson KM, Clegg RM. Observation and quantification of ultraviolet-induced reactive oxygen species in ex vivo human skin. Photochem Photobiol. 2002 Jul;76(1):57-63. doi: 10.1562/0031-8655(2002)0762.0.co;2.
Provided Documents
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Document Type: Study Protocol
Other Identifiers
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1042064
Identifier Type: -
Identifier Source: org_study_id
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