Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
30 participants
INTERVENTIONAL
2026-09-30
2028-09-30
Brief Summary
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Detailed Description
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* Real rTMS or sham rTMS that last about 60 minutes
* Gaze stabilization exercise via a virtual reality headset for about 1-hour
* Target stepping on a treadmill for about 1-hour
Researchers will compare changes in gaze and gait following training sessions with real rTMS and sham rTMS.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
SINGLE
Study Groups
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Real 10 Hz rTMS
Participants will receive 1 hour of real rTMS followed by 1 hour of gaze and gait training.
Repetitive Transcranial Magnetic Stimulation (rTMS)
10 Hz rTMS for 5 seconds over the frontal eye fields with 25 second intertrain interval for 10 trains (500 pulses) at 90% of the resting motor threshold,
Gait training
Subjects will practice stepping on virtual targets with real-time feedback of their foot position displayed on a screen while walking on a treadmill.
Gaze training
Subjects will perform gaze stabilization and gaze shifting exercise via a virtual reality headset.
sham rTMS
Participants will receive 1 hour of sham rTMS followed by 1 hour of gaze and gait training.
Gait training
Subjects will practice stepping on virtual targets with real-time feedback of their foot position displayed on a screen while walking on a treadmill.
Gaze training
Subjects will perform gaze stabilization and gaze shifting exercise via a virtual reality headset.
Sham rTMS
Sham rTMS stimulation will produce discharge noise and vibration without stimulating the cerebral cortex.
Interventions
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Repetitive Transcranial Magnetic Stimulation (rTMS)
10 Hz rTMS for 5 seconds over the frontal eye fields with 25 second intertrain interval for 10 trains (500 pulses) at 90% of the resting motor threshold,
Gait training
Subjects will practice stepping on virtual targets with real-time feedback of their foot position displayed on a screen while walking on a treadmill.
Gaze training
Subjects will perform gaze stabilization and gaze shifting exercise via a virtual reality headset.
Sham rTMS
Sham rTMS stimulation will produce discharge noise and vibration without stimulating the cerebral cortex.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Capable of providing informed consent and complying to the experimental procedures
Exclusion Criteria
* Presence of implanted device such as a neurostimulator, cochlear implant or pacemaker
* History of epilepsy
* History of hearing issues
18 Years
80 Years
ALL
No
Sponsors
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University of Florida
OTHER
Responsible Party
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Principal Investigators
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Julia Choi, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
University of Florida
Other Identifiers
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IRB202300184
Identifier Type: -
Identifier Source: org_study_id
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