Application of Point-of-care Ultrasound in Rapid Assessment of Cardiac Arrest Patients

NCT ID: NCT05859516

Last Updated: 2023-05-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-01

Study Completion Date

2024-06-30

Brief Summary

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To quickly assess the patient's cardiac function and structure through ultrasound

Detailed Description

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Monitor the peripheral arterial pulse and flow velocity, monitor the patient's lung and diaphragm muscle movement, monitor the patient's optic nerve sheath and cerebral blood flow, observe the morphology and blood flow of the liver and kidney and other parenchymal organs, Comprehensive evaluation of patient resuscitation quality.

For patients with cardiac arrest undergoing Cardio Pulmonary Resuscitation (CPR), the above monitoring was completed by ultrasound, and compared with the parameters obtained by end-expiratory carbon dioxide (ETCO2) and compression feedback device, to evaluate the feasibility of ultrasound to evaluate the quality of CPR. After the reliability evaluation was completed, parameters were further used to guide CPR quality improvement through ultrasound, end-expiratory carbon dioxide (ETCO2), and compression feedback device.

Conditions

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Cardiac Arrest Point-of-care Ultrasound Cardiopulmonary Resuscitation

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Experimental: Ultrasound

Ultrasound

Intervention Type DIAGNOSTIC_TEST

Every time checking pulse, evaluate the carotid artery compressibility and blood flow of peripheral arteries by ultrasound,compared with EtCO2.

Interventions

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Ultrasound

Every time checking pulse, evaluate the carotid artery compressibility and blood flow of peripheral arteries by ultrasound,compared with EtCO2.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Voluntarily participate and sign a written informed consent;
* Male or female above 18;
* Patients who are sent to the emergency room of our hospital with symptoms of "cardiopulmonary resuscitation";

Exclusion Criteria

* There is trauma in the ultrasound examination site and it is not suitable for ultrasound examination;
* Entering the emergency room without vital signs for more than 30 minutes;
* The appearance of corpse corpses;
* There is life-threatening and irreversible damage;
* Other investigators consider it inappropriate and the patient or family member refuses;
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zhongnan Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jian Xia, Dr.

Role: PRINCIPAL_INVESTIGATOR

Wuhan University

Locations

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Zhongnan Hospital of Wuhan University

Wuhan, Hubei, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Hao Zou, Dr.

Role: CONTACT

86-27-67813337

Facility Contacts

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Hao Zou

Role: primary

18571618123

References

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Pandor A, Fuller G, Essat M, Sabir L, Holt C, Buckley Woods H, Chatha H. Individual risk factors predictive of major trauma in pre-hospital injured older patients: a systematic review. Br Paramed J. 2022 Mar 1;6(4):26-40. doi: 10.29045/14784726.2022.03.6.4.26.

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PMID: 33496779 (View on PubMed)

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016 Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287.

Reference Type BACKGROUND
PMID: 26903338 (View on PubMed)

Reynolds JC, Nicholson T, O'Neil B, Drennan IR, Issa M, Welsford M; Advanced Life Support Task Force at the International Liaison Committee on Resuscitation ILCOR. Diagnostic test accuracy of point-of-care ultrasound during cardiopulmonary resuscitation to indicate the etiology of cardiac arrest: A systematic review. Resuscitation. 2022 Mar;172:54-63. doi: 10.1016/j.resuscitation.2022.01.006. Epub 2022 Jan 19.

Reference Type BACKGROUND
PMID: 35065210 (View on PubMed)

Montoya J, Stawicki SP, Evans DC, Bahner DP, Sparks S, Sharpe RP, Cipolla J. From FAST to E-FAST: an overview of the evolution of ultrasound-based traumatic injury assessment. Eur J Trauma Emerg Surg. 2016 Apr;42(2):119-26. doi: 10.1007/s00068-015-0512-1. Epub 2015 Mar 14.

Reference Type BACKGROUND
PMID: 26038031 (View on PubMed)

Keikha M, Salehi-Marzijarani M, Soldoozi Nejat R, Sheikh Motahar Vahedi H, Mirrezaie SM. Diagnostic Accuracy of Rapid Ultrasound in Shock (RUSH) Exam; A Systematic Review and Meta-analysis. Bull Emerg Trauma. 2018 Oct;6(4):271-278. doi: 10.29252/beat-060402.

Reference Type BACKGROUND
PMID: 30402514 (View on PubMed)

Dicker SA. Lung Ultrasound for Pulmonary Contusions. Vet Clin North Am Small Anim Pract. 2021 Nov;51(6):1141-1151. doi: 10.1016/j.cvsm.2021.07.001. Epub 2021 Sep 11.

Reference Type BACKGROUND
PMID: 34521570 (View on PubMed)

Lichtenstein D. Fluid administration limited by lung sonography: the place of lung ultrasound in assessment of acute circulatory failure (the FALLS-protocol). Expert Rev Respir Med. 2012 Apr;6(2):155-62. doi: 10.1586/ers.12.13.

Reference Type BACKGROUND
PMID: 22455488 (View on PubMed)

Kang SY, Jo IJ, Lee G, Park JE, Kim T, Lee SU, Hwang SY, Shin TG, Kim K, Shim JS, Yoon H. Point-of-care ultrasound compression of the carotid artery for pulse determination in cardiopulmonary resuscitation. Resuscitation. 2022 Oct;179:206-213. doi: 10.1016/j.resuscitation.2022.06.025. Epub 2022 Jul 2.

Reference Type BACKGROUND
PMID: 35792305 (View on PubMed)

Sheak KR, Wiebe DJ, Leary M, Babaeizadeh S, Yuen TC, Zive D, Owens PC, Edelson DP, Daya MR, Idris AH, Abella BS. Quantitative relationship between end-tidal carbon dioxide and CPR quality during both in-hospital and out-of-hospital cardiac arrest. Resuscitation. 2015 Apr;89:149-54. doi: 10.1016/j.resuscitation.2015.01.026. Epub 2015 Jan 30.

Reference Type BACKGROUND
PMID: 25643651 (View on PubMed)

Genbrugge C, Dens J, Meex I, Boer W, Eertmans W, Sabbe M, Jans F, De Deyne C. Regional Cerebral Oximetry During Cardiopulmonary Resuscitation: Useful or Useless? J Emerg Med. 2016 Jan;50(1):198-207. doi: 10.1016/j.jemermed.2015.03.043. Epub 2015 Sep 26.

Reference Type BACKGROUND
PMID: 26412107 (View on PubMed)

Reynolds JC, Issa MS, C Nicholson T, Drennan IR, Berg KM, O'Neil BJ, Welsford M; Advanced Life Support Task Force of the International Liaison Committee on Resuscitation. Prognostication with point-of-care echocardiography during cardiac arrest: A systematic review. Resuscitation. 2020 Jul;152:56-68. doi: 10.1016/j.resuscitation.2020.05.004. Epub 2020 May 11.

Reference Type BACKGROUND
PMID: 32437781 (View on PubMed)

Kedan I, Ciozda W, Palatinus JA, Palatinus HN, Kimchi A. Prognostic value of point-of-care ultrasound during cardiac arrest: a systematic review. Cardiovasc Ultrasound. 2020 Jan 13;18(1):1. doi: 10.1186/s12947-020-0185-8.

Reference Type BACKGROUND
PMID: 31931808 (View on PubMed)

Other Identifiers

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2022003

Identifier Type: -

Identifier Source: org_study_id

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