Predictors of Chronic Kidney Disease Among Type 2 Diabetic Patients in Assiut University Hospitals

NCT ID: NCT05847400

Last Updated: 2023-05-06

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 200 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-03-01
• Study Completion Date: 2024-04-01

Brief Summary

Predictors of Chronic Kidney Disease among Type 2 Diabetic Patients in Assiut University Hospitals.

Detailed Description

Globally, the total number of people with diabetes is estimated to increase from 415 million (8.8%) in 2015 to 642 million (10.4%) in 2040, with the largest alterations expected to occur in the urban population of low- to middle-income countries (LMICs)1. Of them, type 2 diabetes mellitus (T2DM) accounts for more than 90% of people with diabetes2,3. By 2040, the difference worldwide is projected to broaden, with 477.9 million affected people living in urban areas and 163.9 million in rural areas1. It has been postulated that the burden of diabetes and its complications in the LMICs may be contributed by the economic development and rapid urbanisation via increased caloric intake and the adoption of a sedentary lifestyle2,4,5. More importantly, the most striking demo graphic change to diabetes prevalence in global terms also seems to be related to the growth of the proportion of the elderly population6. Despite rates of diabetes-related complications such as CVDs decreasing significantly in the past two decades, it has not translated nearly as well as kidney complications7. Approximately 10% of deaths in people with T2DM are attributable to kidney failure8. It is well-established that diabetes-related chronic kidney disease (CKD) is the leading cause of end-stage kidney disease (ESKD) in T2DM patients worldwide9,10.

In our study, we aim to identify and classify patients attending diabetic outpatient clinic with both CKD and

Conditions

Type 2 Diabetes With Renal Manifestations

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

CKD patients with T2DM on regular HD

CKD patients with T2DM attending Assuit university diabetic outpatients clinic and ESRD on regular HD at dialysis unit of Assuit University Hospital

No interventions assigned to this group

CKD patients with T2DM not on regular HD

CKD patients with T2DM attending Assuit university diabetic outpatients clinic and ESRD not on regular HD at dialysis unit of Assuit University Hospital

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Patients with T2DM aged 18 years or older. For patients whom eGFR values < or =60 ml/min/1.73m2.

Patient with type 2 DM and ESRD on regular HD with duration less than 1 year

Exclusion Criteria

Having kidney transplantation incomplete data on glycemic control. Patients with type 2 DM and ESRD on regular HD with duration more than 1 year. Pregnant woman. Patients with advanced comorbides(cardiac, hepatic,

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Muhammed Ali Aboalsaud

Aboalsaud

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Muhammed Al Abualsaud

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Locations

Assiut

Asyut, , Egypt

Site Status: RECRUITING

Countries

Egypt

Central Contacts

Muhammed Al Abualsaud

Role: CONTACT

Aboalsaud25@gmail.com

‪+20 106 923 9438‬

Peter At Munir

Role: CONTACT

01553529181

Facility Contacts

Muhammed Al Abualsaud, Master

Role: primary

Aboalsaud25@gmail.com

‪+20 106 923 9438‬

Peter At Munir

Role: backup

01553529181

Other Identifiers

ckd in tybe 2 dm

Identifier Type: -

Identifier Source: org_study_id