Intraoperative Methadone for Postoperative Pain Control
NCT ID: NCT05845359
Last Updated: 2023-10-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
PHASE4
INTERVENTIONAL
2023-09-30
2024-02-29
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Methadone group
Patients in this group will receive intraoperative methadone.
Methadone
One group will receive 10mg of methadone upon induction, while the other will receive a saline solution as placebo. We will see the effectiveness of methadone on postoperative pain management, while monitoring for opioid-related side effects.
Control group
Patients in this group will receive saline (placebo), instead of methadone
No interventions assigned to this group
Interventions
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Methadone
One group will receive 10mg of methadone upon induction, while the other will receive a saline solution as placebo. We will see the effectiveness of methadone on postoperative pain management, while monitoring for opioid-related side effects.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Patients with BMI \>60
* AHI \> 30 (AHI = Apnea-Hypopnea Index), indicative of severe Obstructive Sleep Apnea (OSA)
* ASA IV or V (American Society of Anesthesiology physical status classification system)
* Patients taking opioids for chronic conditions in the last 10 days preceding the surgery
* Patients currently being treated for chronic opioid addiction
* Patients with severe psychiatric diagnoses
* Allergies to medications used in protocol
18 Years
60 Years
ALL
No
Sponsors
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Montefiore Medical Center
OTHER
Responsible Party
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Principal Investigators
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Jennifer Choi, MD
Role: PRINCIPAL_INVESTIGATOR
Montefiore Medical Center
Other Identifiers
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2022-14040
Identifier Type: -
Identifier Source: org_study_id
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