AMNIOmics: A Prenatal Rapid Genome Validation Study

NCT ID: NCT05834621

Last Updated: 2025-09-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-07

Study Completion Date

2025-01-07

Brief Summary

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The purpose of this study is to validate Whole Genome Sequencing (WGS) on amniotic fluid to reduce the time to diagnosis and enhance the care for the fetus/neonate.

Detailed Description

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Conditions

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Multiple Anomalies of Fetus Genetic Predisposition Suspected Amniocentesis Affecting Fetus or Newborn Family Members

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* Fetus with multiple anomalies/suspected genetic disease.
* Pregnant patient already planning on having an amniocentesis for another reason separate from this study.

Exclusion Criteria

* Parents under the age of 18.
* Parents lacking the capacity to consent.
* Institutionalized (i.e., Federal Medical Prison).
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Myra J. Wick

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Myra Wick, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Related Links

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Other Identifiers

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22-002719

Identifier Type: -

Identifier Source: org_study_id

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