The Effect of Lullaby and Breastmilk Smell on Preterm Newborns

NCT ID: NCT05830955

Last Updated: 2024-03-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

57 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-15

Study Completion Date

2024-03-05

Brief Summary

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The goal of this clinical trial is to investigate the effect of live lullaby from mother voice, and breast milk smell on pyhsiological parameters, comfort and maternal attachment levels of preterm newborns who are between 35-37 weeks of gestation at the time of the study and the level of pospartum depression of mothers. The main hypothesis are:

H0: The live lullaby from mother voice and breast milk smell have no effects on pyhsiological parameters, comfort and maternal attachment levels of preterm newborns H1: The live lullaby from mother voice has effects on pyhsiological parameters, comfort and maternal attachment levels of preterm newborns H2: The breast milk smell has effects on pyhsiological parameters, comfort and maternal attachment levels of preterm newborns H3: There is differences between the live lullaby from mother voice and the breast milk smell interventions in terms of preterm newborns' physiological parameters, comfort and maternal attachment levels.

H4: The postpartum depression level of mothers in experimental groups (lullaby group and breast milk group) is lower than the control group.

Participants will be in three groups according to the interventions. The preterm newborns who are going to listen a live lullaby from their mothers' voice will be the first group (Lullaby group). The preterms in the second group (Breast milk group) are going to smell their mothers' breast milk. The preterms in the third group (Control group) are going to recieve rutin nursing care interventions.

Detailed Description

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Conditions

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Preterm Infant, Premature, Diseases Postpartum Depression Mother-Infant Interaction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Participants will be in three groups according to the interventions. The preterm newborns who are going to listen a live lullaby from their mothers' voice will be the first group (Lullaby group). The preterms in the second group (Breast milk group) are going to smell their mothers' breast milk. The preterms in the third group (Control group) are going to recieve rutin nursing care interventions.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Lullaby Group

The preterm newborns who are going to listen a live lullaby from their mothers' voice will be the first group (Lullaby group).

Group Type EXPERIMENTAL

Lullaby group

Intervention Type OTHER

The preterm newborns who are going to listen a live lullaby from their mothers' voice will be the first group (Lullaby group).

Breast milk Group

The preterms in the second group (Breast milk group) are going to smell their mothers' breast milk.

Group Type EXPERIMENTAL

Breast milk group

Intervention Type OTHER

The preterms in the second group (Breast milk group) are going to smell their mothers' breast milk.

Control Group

The preterms in the third group (Control group) are going to recieve rutin nursing care interventions.

Group Type OTHER

Control group

Intervention Type OTHER

The preterms in the third group (Control group) are going to recieve rutin nursing care interventions.

Interventions

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Lullaby group

The preterm newborns who are going to listen a live lullaby from their mothers' voice will be the first group (Lullaby group).

Intervention Type OTHER

Breast milk group

The preterms in the second group (Breast milk group) are going to smell their mothers' breast milk.

Intervention Type OTHER

Control group

The preterms in the third group (Control group) are going to recieve rutin nursing care interventions.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Parents' willingness to participate in the study
* Turkish literate parents
* Babies between 35-37 weeks of gestation
* Apgar score of 7 or higher at birth
* Stability of the baby (near discharge)
* Having mother's milk

Exclusion Criteria

* Parents' reluctance to participate in the study
* Babies younger than 35 weeks and older than 37 weeks
* Babies receiving phototherapy
* Finding a congenital anomaly in infants
* Apgar score below 7 at birth
* Being connected to a mechanical ventilator
Minimum Eligible Age

35 Weeks

Maximum Eligible Age

37 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Istanbul University - Cerrahpasa

OTHER

Sponsor Role collaborator

Yuzuncu Yıl University

OTHER

Sponsor Role collaborator

Van Training and Research Hospital

OTHER_GOV

Sponsor Role collaborator

Mustafa Kemal University

OTHER

Sponsor Role lead

Responsible Party

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Gizem Kerimoğlu Yıldız

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Van Training and Research Hospital

Van, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Rattaz C, Goubet N, Bullinger A. The calming effect of a familiar odor on full-term newborns. J Dev Behav Pediatr. 2005 Apr;26(2):86-92. doi: 10.1097/00004703-200504000-00003.

Reference Type BACKGROUND
PMID: 15827459 (View on PubMed)

Namjoo R, Mehdipour-Rabori R, Bagherian B, Nematollahi M. Comparing the effectiveness of mother's live lullaby and recorded lullaby on physiological responses and sleep of preterm infants: a clinical trial study. J Complement Integr Med. 2021 May 24;19(1):121-129. doi: 10.1515/jcim-2020-0507.

Reference Type BACKGROUND
PMID: 34022122 (View on PubMed)

Cignacco E, Hamers JP, van Lingen RA, Zimmermann LJ, Muller R, Gessler P, Nelle M. Pain relief in ventilated preterms during endotracheal suctioning: a randomized controlled trial. Swiss Med Wkly. 2008 Nov 1;138(43-44):635-45. doi: 10.4414/smw.2008.12288.

Reference Type BACKGROUND
PMID: 19005869 (View on PubMed)

Lessen Knoll BS, Daramas T, Drake V. Randomized Controlled Trial of a Prefeeding Oral Motor Therapy and Its Effect on Feeding Improvement in a Thai NICU. J Obstet Gynecol Neonatal Nurs. 2019 Mar;48(2):176-188. doi: 10.1016/j.jogn.2019.01.003. Epub 2019 Feb 2.

Reference Type BACKGROUND
PMID: 30721652 (View on PubMed)

da Silva CM, Cacao JM, Silva KC, Marques CF, Merey LS. Physiological responses of preterm newborn infants submitted to classical music therapy. Rev Paul Pediatr. 2013 Jan-Mar;31(1):30-6. doi: 10.1590/s0103-05822013000100006. English, Portuguese.

Reference Type BACKGROUND
PMID: 23703041 (View on PubMed)

Cox JL, Holden JM, Sagovsky R. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br J Psychiatry. 1987 Jun;150:782-6. doi: 10.1192/bjp.150.6.782.

Reference Type BACKGROUND
PMID: 3651732 (View on PubMed)

Aydin N, Inandi T, Yigit A, Hodoglugil NN. Validation of the Turkish version of the Edinburgh Postnatal Depression Scale among women within their first postpartum year. Soc Psychiatry Psychiatr Epidemiol. 2004 Jun;39(6):483-6. doi: 10.1007/s00127-004-0770-4.

Reference Type BACKGROUND
PMID: 15205733 (View on PubMed)

Kurt FY, Kucukoglu S, Ozdemir AA, Ozcan Z. The effect of kangaroo care on maternal attachment in preterm infants. Niger J Clin Pract. 2020 Jan;23(1):26-32. doi: 10.4103/njcp.njcp_143_18.

Reference Type BACKGROUND
PMID: 31929203 (View on PubMed)

Loewy J, Stewart K, Dassler AM, Telsey A, Homel P. The effects of music therapy on vital signs, feeding, and sleep in premature infants. Pediatrics. 2013 May;131(5):902-18. doi: 10.1542/peds.2012-1367. Epub 2013 Apr 15.

Reference Type BACKGROUND
PMID: 23589814 (View on PubMed)

Alipour Z, Eskandari N, Ahmari Tehran H, Eshagh Hossaini SK, Sangi S. Effects of music on physiological and behavioral responses of premature infants: a randomized controlled trial. Complement Ther Clin Pract. 2013 Aug;19(3):128-32. doi: 10.1016/j.ctcp.2013.02.007. Epub 2013 May 9.

Reference Type BACKGROUND
PMID: 23890458 (View on PubMed)

Taheri L, Jahromi MK, Abbasi M, Hojat M. Effect of recorded male lullaby on physiologic response of neonates in NICU. Appl Nurs Res. 2017 Feb;33:127-130. doi: 10.1016/j.apnr.2016.11.003. Epub 2016 Nov 9.

Reference Type BACKGROUND
PMID: 28096005 (View on PubMed)

Other Identifiers

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Hatay Mustafa Kemal University

Identifier Type: -

Identifier Source: org_study_id

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