GAE Using Embosphere Microspheres vs Corticosteroid Injections for Treatment of Symptomatic Knee OA (MOTION)
NCT ID: NCT05818150
Last Updated: 2025-10-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
ACTIVE_NOT_RECRUITING
NA
264 participants
INTERVENTIONAL
2024-01-16
2027-10-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Randomized Controlled Study Evaluating Genicular Artery Embolization Against Intra-Articular Corticosteroid Knee Injection for Osteoarthritic Knee Pain
NCT06872567
Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis
NCT05112926
Genicular Artery Embolization (GAE) vs inTra-articular Corticosteroid Injection for Osteoarthritic Knee Pain.
NCT06929585
Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis
NCT06859164
Genicular Artery Embolisation for Knee Osteoarthritis II
NCT05423587
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Genicular artery embolization with Embosphere Microspheres
Device: Embosphere Microspheres
Embolic Agent: Embosphere Microspheres
Embosphere Microspheres
Embolic Agent: Embosphere Microspheres
Corticosteroid Injection of the knee
Drug: Corticosteroid injection
Corticosteroid injection
Corticosteroid injection
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Embosphere Microspheres
Embolic Agent: Embosphere Microspheres
Corticosteroid injection
Corticosteroid injection
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Age ≥21 years
Mild to severe knee pain, defined as a WOMAC Pain score of ≥8 out of 20 (in the target knee)
Pain refractory to conservative therapies for at least 90 days prior to enrollment/randomization.
Kellgren-Lawrence grade 1, 2, 3 or 4
Exclusion Criteria
Advanced atherosclerosis
Known history of rheumatoid or infectious arthritis.
Prior knee replacement surgery of the target knee.
21 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Merit Medical Systems, Inc.
INDUSTRY
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Sandeep Bagla, MD
Role: PRINCIPAL_INVESTIGATOR
Prostate Centers, USA
Craig J McAsey, MD
Role: PRINCIPAL_INVESTIGATOR
Anderson Orthopedic Clinic
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Memorial Care Long Beach Medical Center
Long Beach, California, United States
Georgetown University Medical Center
Washington D.C., District of Columbia, United States
MedStar Washington Hospital Center
Washington D.C., District of Columbia, United States
Emory University School of Medicine
Atlanta, Georgia, United States
Biotech Clinical Research/ Georgia Vascular Institute
College Park, Georgia, United States
Northwestern University
Chicago, Illinois, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
Saint Louis University
St Louis, Missouri, United States
Atlantic Medical Imaging
Galloway, New Jersey, United States
Rutgers Health
Newark, New Jersey, United States
Northwell Health
Manhasset, New York, United States
Weill Cornell Medicine
New York, New York, United States
Atlas Interventional
Williamsville, New York, United States
Prostate Centers USA
Raleigh, North Carolina, United States
Sunrise Vascular Center
Sanford, North Carolina, United States
The Ohio State University
Columbus, Ohio, United States
Cardiovascular Health Clinic
Oklahoma City, Oklahoma, United States
Prostate Centers USA
Falls Church, Virginia, United States
Prostate Centers USA
Leesburg, Virginia, United States
Liverpool Hospital
Liverpool, , Australia
Hospital de Clínicas de Passo Fundo
Passo Fundo, , Brazil
University of Sao Paulo
São Paulo, , Brazil
Vancouver General Hospital
Vancouver, British Columbia, Canada
CHUM - Centre hospitalier de l'Université de Montréal
Montreal, , Canada
North Shore Hospital/ Te Whatu Ora - Waitemata
Takapuna, , New Zealand
University Hospitals Dorset
Bournemouth, , United Kingdom
Grange University Hospital
Cwmbran, , United Kingdom
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Bent C, McAsey CJ, Bagla S. Multicenter, PrOspective, Randomized, Controlled Trial Comparing GenIcular Artery EmbOlization Using Embosphere Microspheres to Corticosteroid iNjections for the Treatment of Symptomatic Knee Osteoarthritis: MOTION Study Protocol Summary. Cardiovasc Intervent Radiol. 2025 Apr;48(4):551-558. doi: 10.1007/s00270-025-03994-z. Epub 2025 Mar 6.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
GAE-P3-22-01
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.