Strategic Use of Big Data in Spine Surgery - Testing Digital Prediction of Outcome in Clinical Praxis

NCT ID: NCT05817747

Last Updated: 2025-05-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

900 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-01

Study Completion Date

2029-03-01

Brief Summary

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The goal of this prospective, multicenter clinical trial is to determine if the use of the postoperative outcome prediction model the Dialogue Support tool can alter postoperative patient-reported outcome and satisfaction compared to current practice.

The main questions it aims to answer are:

* Does its use alter patient-reported outcome measured by general assessment regarding leg pain and Satisfaction in lumbar spinal stenosis?
* Does its use alter patient-reported outcome as measured by general assessment regarding arm pain and Satisfaction in cervical rhizopathy?
* How does the Quality of Life in patients - who after assessment by spinal surgeon do not proceed to surgery - compare with patients with the same baseline profile who did undergo surgery?

Eligible participants will be presented with their predicted postoperative outcome generated by the Dialogue Support tool, as an adjunct to the ordinary assessment by a spine surgeon.

Researchers will compare participants with a matched control group from the Swedish Spine Register ("Swespine") to see if the Dialogue Support tool can alter postoperative patient-reported outcome and satisfaction.

Detailed Description

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Conditions

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Constriction, Pathologic Spine Degeneration Surgery Radiculopathy

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

On all participants the dialogue support tool will be used and will thereafter be put into either of two treatment-arms (surgical, or non-surgical treatment)
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Surgery

Participants will after the dialogue support tool has been undergo surgery.

Group Type EXPERIMENTAL

Dialogue support tool

Intervention Type OTHER

The dialogue support tool will be used as a support for the participant and surgeon to decide on which treatment arm is optimal for the participant.

Non-surgery

Participants will after the dialogue support tool has been used not undergo surgery.

Group Type PLACEBO_COMPARATOR

Dialogue support tool

Intervention Type OTHER

The dialogue support tool will be used as a support for the participant and surgeon to decide on which treatment arm is optimal for the participant.

Interventions

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Dialogue support tool

The dialogue support tool will be used as a support for the participant and surgeon to decide on which treatment arm is optimal for the participant.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Refered to a participating clinic regarding surgery for lumbar spinal stenosis or cervical radiculopathy
* 18 years of age or older
* Magnetic Resonance Imaging (MRT) examination within the last 12 months confirming the diagnosis, concurrent with symptoms described by the referring physician
* Giving informed consent

Exclusion Criteria

* Another condition found to be the reason for the symptoms.
* Not giving informed consent
* Need for further investigation that prevents inclusion within one month of the doctor visit.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sahlgrenska University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Catharina Parai, MD, PhD

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Catharina Parai, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Sahlgrenska University Hospital

Locations

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Aleris Ortopedi Ängelholm

Ängelholm, Skåne County, Sweden

Site Status RECRUITING

Aleris Ortopedi Malmö

Malmo, Skåne County, Sweden

Site Status ACTIVE_NOT_RECRUITING

Sahlgrenska University Hospital

Gothenburg, Västra Götaland County, Sweden

Site Status RECRUITING

Spine Center Göteborg

Gothenburg, Västra Götaland County, Sweden

Site Status RECRUITING

Ryggkirurgiskt Centrum

Stockholm, , Sweden

Site Status RECRUITING

Spine Center Stockholm

Stockholm, , Sweden

Site Status RECRUITING

Sundsvalls sjukhus

Sundsvall, , Sweden

Site Status RECRUITING

Norrland University Hospital

Umeå, , Sweden

Site Status RECRUITING

Uppsala University Hospital

Uppsala, , Sweden

Site Status RECRUITING

Aleris Elisabethsjukhuset

Uppsala, , Sweden

Site Status ACTIVE_NOT_RECRUITING

Countries

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Sweden

Central Contacts

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Catharina Parai, MD, PhD

Role: CONTACT

0046313421000

Eric Brisby Enger, MD

Role: CONTACT

0046735716723

Facility Contacts

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Anders Kjellin, MD

Role: primary

Catharina Parai, MD, PhD

Role: primary

0046313421000

Kajsa Rennerfelt, MD, PhD

Role: primary

Per Svedmark, MD,PhD

Role: primary

Konstantinos Pazarlis, MD

Role: primary

Björn Knutsson, MD, PhD

Role: primary

Johan Wenman, MD, PhD

Role: primary

0046702698300

Anna Mac Dowall, MD, PhD

Role: primary

References

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Enger EB, Valentin-Askman L, Hagg O, Fritzell P, Parai C. The strategic use of Big Data - A study protocol for a multicenter clinical trial testing if the use of the Swespine Dialogue Support alter outcomes in degenerative spine surgery. BMC Musculoskelet Disord. 2024 Aug 21;25(1):654. doi: 10.1186/s12891-024-07714-5.

Reference Type DERIVED
PMID: 39169349 (View on PubMed)

Other Identifiers

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2022-2025

Identifier Type: -

Identifier Source: org_study_id

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