Measurement and Analysis of Gas Composition in Digestive Tract

NCT ID: NCT05810805

Last Updated: 2023-04-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

460 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-01

Study Completion Date

2024-03-02

Brief Summary

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The purpose of this study is to detect the concentration of various gases,including hydrogen, methane, hydrogen sulfide, nitric oxide in different parts of the digestive tract by a safe and direct method, and to establish a human digestive tract gas profiles. Analyze the differences in gas components in different segments of the digestive tract in patients with different diseases, and analyze the correlation between specific gases and digestive tract diseases and non-specific symptoms.

Detailed Description

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Conditions

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Inflammatory Bowel Diseases Irritable Bowel Syndrome Functional Dyspepsia Colorectal Neoplasms Helicobacter Pylori Infection

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Control group

gas component of digestive tract

Intervention Type OTHER

Analyze the differences in gas components in different segments of the digestive tract in patients with different diseases, and analyze the correlation between specific gases and digestive tract diseases and non-specific symptoms.

Imflammtory bowel disease group

gas component of digestive tract

Intervention Type OTHER

Analyze the differences in gas components in different segments of the digestive tract in patients with different diseases, and analyze the correlation between specific gases and digestive tract diseases and non-specific symptoms.

Irritable bowel syndrome group

gas component of digestive tract

Intervention Type OTHER

Analyze the differences in gas components in different segments of the digestive tract in patients with different diseases, and analyze the correlation between specific gases and digestive tract diseases and non-specific symptoms.

Colorectal neoplasms group

gas component of digestive tract

Intervention Type OTHER

Analyze the differences in gas components in different segments of the digestive tract in patients with different diseases, and analyze the correlation between specific gases and digestive tract diseases and non-specific symptoms.

Helicobacter pylori infection group

gas component of digestive tract

Intervention Type OTHER

Analyze the differences in gas components in different segments of the digestive tract in patients with different diseases, and analyze the correlation between specific gases and digestive tract diseases and non-specific symptoms.

functional dyspepia group

gas component of digestive tract

Intervention Type OTHER

Analyze the differences in gas components in different segments of the digestive tract in patients with different diseases, and analyze the correlation between specific gases and digestive tract diseases and non-specific symptoms.

Interventions

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gas component of digestive tract

Analyze the differences in gas components in different segments of the digestive tract in patients with different diseases, and analyze the correlation between specific gases and digestive tract diseases and non-specific symptoms.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 to 70 years.
* Patients undergoing endoscopic examination

Exclusion Criteria

* Patients with serious underlying diseases, such as liver insufficiency, renal insufficiency, immunosuppression, coronary heart disease (angina pectoris or coronary artery stenosis ≥ 75%).
* Patients have history of gastrointestinal surgery
* Patients who failed to complete the endoscopic examination due to various reasons
* Patients Boston score of Bowel preparation≤ 6 points
* Patients who have medication history of probiotics, antibiotics, PPIs and prokinetic drugs in the last 4 weeks
* Patients who combined with thyroid disease and other diseases that affect gastrointestinal motility
* Patients who combined with other risk factors such as mental illness, alcoholism, and drug abuse
* Patients who unable or unwilling to provide informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Xiuli Zuo

OTHER

Sponsor Role lead

Responsible Party

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Xiuli Zuo

director of Qilu Hospital gastroenterology department

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Qilu Hospital, Shandong University

Jinan, Shandong, China

Site Status

Countries

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China

Other Identifiers

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2023SDU-QILU-G001

Identifier Type: -

Identifier Source: org_study_id

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