Study of Alpha-blockers Alone During Preoperative Preparation in Patients With Pheochromocytoma
NCT ID: NCT05803330
Last Updated: 2023-04-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
95 participants
INTERVENTIONAL
2014-02-20
2022-10-20
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
NONE
Study Groups
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PXB combined with venous dilation group
Use of PXB combined with intravenous volume expansion during preoperative preparation in patients with pheochromocytoma
No interventions assigned to this group
PXB group
PXB alone during preoperative preparation in patients with pheochromocytoma
Abandonment of intravenous volume expansion during preoperative preparation in patients with pheochromocytoma
Abandonment of intravenous volume expansion with alpha-blockers during preoperative preparation in patients with pheochromocytoma
Interventions
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Abandonment of intravenous volume expansion during preoperative preparation in patients with pheochromocytoma
Abandonment of intravenous volume expansion with alpha-blockers during preoperative preparation in patients with pheochromocytoma
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
85 Years
ALL
No
Sponsors
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Kunwu Yan,MM
OTHER
Responsible Party
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Kunwu Yan,MM
Research Project Leader
Principal Investigators
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kunwu yan, Master
Role: PRINCIPAL_INVESTIGATOR
Handan First Hospital
References
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Meijs AC, Snel M, Corssmit EPM. Pheochromocytoma/paraganglioma crisis: case series from a tertiary referral center for pheochromocytomas and paragangliomas. Hormones (Athens). 2021 Jun;20(2):395-403. doi: 10.1007/s42000-021-00274-6. Epub 2021 Feb 11.
Challis BG, Casey RT, Simpson HL, Gurnell M. Is there an optimal preoperative management strategy for phaeochromocytoma/paraganglioma? Clin Endocrinol (Oxf). 2017 Feb;86(2):163-167. doi: 10.1111/cen.13252. Epub 2016 Oct 24.
Randle RW, Balentine CJ, Pitt SC, Schneider DF, Sippel RS. Selective Versus Non-selective alpha-Blockade Prior to Laparoscopic Adrenalectomy for Pheochromocytoma. Ann Surg Oncol. 2017 Jan;24(1):244-250. doi: 10.1245/s10434-016-5514-7. Epub 2016 Aug 25.
Bihain F, Nomine-Criqui C, Guerci P, Gasman S, Klein M, Brunaud L. Management of Patients with Treatment of Pheochromocytoma: A Critical Appraisal. Cancers (Basel). 2022 Aug 9;14(16):3845. doi: 10.3390/cancers14163845.
Other Identifiers
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202303-1
Identifier Type: -
Identifier Source: org_study_id
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