The Impact of Preoperative Supplementation of Zinc

NCT ID: NCT05785013

Last Updated: 2024-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

1 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-01

Study Completion Date

2023-07-02

Brief Summary

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1. Pre operative anthropometric assessment including : weight in kg, height/length and BMI
2. Pre operative Zinc supplementation (dose according to the age) for 7 days preoperatively for cases
3. Postoperative data collection

Detailed Description

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Postoperative data collection :

* Length of hospital stay
* Complication and sorting of them
* Lab withdrawal of inflammatory markers on 2-3 day postoperatively

Conditions

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Surgery Nutrition Disorders

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Caregivers

Study Groups

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Interventional

25 children diagnosed with Hirschsprung disease and planned for elective surgery will be supplemented with Zinc 7 days before the operation . Outcomes will be evaluated thorugh measuring the hospital length stay. Other parameters including inflammatory markers as CRP , CRP /albumin ratio and development of postoperative complications will be assesed and compared between cases and controls

Group Type EXPERIMENTAL

Zinc

Intervention Type DIETARY_SUPPLEMENT

Zinc Supplementation

Control

25 children diagnosed with Hirschsprung disease and planned for elective surgery will recieve the standard care provided for the cases and will not be supplemented with Zinc . Outcomes will be evaluated thorugh measuring the hospital length. Other parameters including inflammatory markers as CRP , CRP /albumin ratio and development of postoperative complications will be assesed and compared between cases and controls

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Zinc

Zinc Supplementation

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

1. All children patients with Hirschsprung disease admitted for surgical intervention with different ( age , sex )
2. Type of surgery : transanal pull through
3. Whose parents or caregivers approve for the participation in the study

Exclusion Criteria

1. Patients with emergency situations
2. Whose parents or caregivers will not apply for the participation in the study
Minimum Eligible Age

1 Month

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Hoda Atef Abdelsattar Ibrahim

Lecturer of Pediatrics

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Hoda Atef Abdelsattar Ibrahim

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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MS 277-2022

Identifier Type: -

Identifier Source: org_study_id

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