Study of Bronchiectasis and Associated Cardiovascular Comorbidities

NCT ID: NCT05783869

Last Updated: 2025-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-03-25

Study Completion Date

2026-11-01

Brief Summary

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Effect of cardiovascular comorbidities on disease severity and quality of life in Patients with acute exacerbation of non-cystic fibrosis bronchiectasis

Detailed Description

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The study will include patients with bronchiectasis, and in an attempt to correlate the effect and burden of cardiovascular comorbidities in those patients, we will study the quality of life in those patients in comparison to the control group ( patients with bronchiectasis and without any other comorbidities) using SF-36 quality of life questionnaire. We will also study the inflammatory markers in both groups using D-dimer, BNP, and CRP and correlate them with the frequency of hospital admission, the severity of symptoms, and the general health state.

Conditions

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Bronchiectasis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patient with bronchiectasis and cardiovascular comorbidities

Patients with Bronchiectasis had no comorbidities other than cardiovascular comorbidities during the study period.

Echocardiography

Intervention Type DEVICE

echocardiographic study of both groups

Patients with bronchiectasis and without cardiovascular comorbidities

Patients with Bronchiectasis had no comorbidities.

Echocardiography

Intervention Type DEVICE

echocardiographic study of both groups

Interventions

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Echocardiography

echocardiographic study of both groups

Intervention Type DEVICE

Other Intervention Names

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Pulmonary function test Routine laboratory investigations and inflammatory markers

Eligibility Criteria

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Inclusion Criteria

• Any Patients with Bronchiectasis had no comorbidities other than cardiovascular comorbidities during the study period.

Exclusion Criteria

* Any Patients who refuse to participate in the study.
* Any other comorbidity or end-organ failure may affect the study's result.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aliae AR Mohamed Hussein [ahussein

UNKNOWN

Sponsor Role collaborator

Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Ahmad Shaddad

Lecturer of pulmonary medicine Assuit university

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmad Shaddad

Role: PRINCIPAL_INVESTIGATOR

Assuit University Faculty of Medicine

Ahmad Shaddad

Role: PRINCIPAL_INVESTIGATOR

Assiut University Faculty of Medicine

Locations

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Assiut unviresty - Faculty of Medicine

Asyut, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Shaadad Shaddad, MD

Role: CONTACT

+201111171930

Ahmad Shaddad, MD

Role: CONTACT

+201111171930

Facility Contacts

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Ahmad Shaddad, Lecturer

Role: primary

+201111171930

Other Identifiers

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23455668

Identifier Type: -

Identifier Source: org_study_id

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