Cluster-Randomized Trial of Air Filtration and Ventilation to Reduce Covid19 Spread in Homes
NCT ID: NCT05777720
Last Updated: 2025-06-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ENROLLING_BY_INVITATION
NA
200 participants
INTERVENTIONAL
2023-01-30
2025-12-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
SINGLE_GROUP
PREVENTION
NONE
Study Groups
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Control
No intervention will be administered in this arm. Investigators will give families a CO2 monitor to measure average CO2 levels in the home. Investigators will provide a link to the basic CDC isolation guidelines which would be part of standard of care. Investigators will test family members at day 0-1 for baseline testing; and again on day 7 for assessing secondary transmission among susceptible contacts.
No interventions assigned to this group
Intervention
Families are provided with one filtration fan unit per room in their home (and one for the index case; if the family lives in a studio, they would receive 2 units). Investigators will advise families on ventilation improvements in their home. Investigators will provide an instructional pamphlet that describes how the fans work and the importance of ventilation. Investigators will follow-up on day 3-4 to check in and run through a checklist to ensure the fans are working and ventilation improvements are being attempted. Investigators will give families a CO2 monitor to measure average CO2 levels in the home. Investigators will test family members at day 0-1 for baseline testing; and again on day 7 for assessing secondary transmission among susceptible contacts.
Filtration Fan
Investigators are using box fans with attached MERV16 filters, a design that has been tested and published in the scientific literature.
Safe-home pamphlet
The pamphlet has information on how the filtration fans work through visual images; and images of ventilation improvements in the home through opening windows.
Mid-week phone call
On day 3-4 of the study, the study coordinator assigned to the house will call and check in regarding the filtration fan usage and remind families about the importance of filtration and ventilation.
Interventions
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Filtration Fan
Investigators are using box fans with attached MERV16 filters, a design that has been tested and published in the scientific literature.
Safe-home pamphlet
The pamphlet has information on how the filtration fans work through visual images; and images of ventilation improvements in the home through opening windows.
Mid-week phone call
On day 3-4 of the study, the study coordinator assigned to the house will call and check in regarding the filtration fan usage and remind families about the importance of filtration and ventilation.
Eligibility Criteria
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Inclusion Criteria
* At least 3 other people live in the household aside from index case
Exclusion Criteria
* If half or more household members are thought to be infected already
* If household has fewer than 3 contacts interested in participating in the study
* If fewer than 3 contacts are expected to be present in the house for a majority of the following 7 days
ALL
Yes
Sponsors
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National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Stanford University
OTHER
Responsible Party
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Abraar Karan
Post-Doctoral Fellow
Principal Investigators
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Yvonne Maldonado, MD
Role: STUDY_DIRECTOR
Stanford University
Abraar Karan, MD
Role: PRINCIPAL_INVESTIGATOR
Stanford University
Locations
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San Mateo Medical Center
San Mateo, California, United States
Stanford University Medical Center
Stanford, California, United States
Countries
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Other Identifiers
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55479
Identifier Type: -
Identifier Source: org_study_id
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