Performance of the Echopen Probe in Its Clinical Use for Pregnancy Follow-up in Senegal

NCT ID: NCT05765539

Last Updated: 2025-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

224 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-29

Study Completion Date

2025-06-19

Brief Summary

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Pregnancy follow-up in a country with limited resources in decentralized areas usually consists of a clinical examination exclusively because of a lack of access to additional examination equipment and qualified personnel to use them. However, the pregnancy follow-up relies in part on the visual investigation by ultrasound scanners that estimate the risks of morbi-mortality for the mother and child during and after pregnancy. The WHO recommendations support at least one ultrasound before 24 weeks of amenorrhea. Thus, at the same time as a usual clinical examination, the possibility of visually assessing certain relevant criteria would help to increase the effectiveness of follow-up visits without complicating the care journey. A simple ultra-portable device would be an opportunity for caregivers to facilitate the detection of complications and thus offer a more adapted follow-up and orientation.

This would allow, in contexts where resources are limited, to improve monitoring and limit the risks of complications due to inappropriate management.

Detailed Description

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The echOpen O1 Ultrasound Probe is a medical device designed to guide the diagnosis during clinical examination by providing a non-invasive, non-irradiant inside body image.

The investigator's hypothesis is that the use of this ultrasound stethoscopy probe during pregnancy, by a trained midwife, would improve the development and outcome of pregnancy for women by identifying situations requiring specificity. Through this protocol, the investigators propose a pilot study to evaluate, under field conditions, the performance of the echOpen O1 probe as part of the 3rd-trimester pregnancy monitoring, compared to a standard ultrasound examination, routinely performed with an ultrasound machine.

The main objective of this prospective pilot study is to evaluate the performance and operationality of the echOpen O1 probe from the 37th week of amenorrhea.

The secondary objectives are :

* To evaluate the feasibility and usability of the echOpen O1 probe in the context of pregnancy monitoring by midwives and in zone field conditions:

* One urban health center (Centralized)
* One rural health center (Decentralized)
* Assess women's quality of life during pregnancy and obtain satisfaction with echOpen O1 probe.

Conditions

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Pregnancy Related

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

A single group, comparative, non-randomized, controlled study. Each patient represents her/his own control: the patient is examined consecutively with the echOpen probe, then with the probe used in the department.
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Midwife 'A' will begin by using either the echOpen probe or the classic US machine (in a random order, via sealed envelopes), and will then carry out the other type of examination. The results book will be filled in and validated after each examination, and it will not be possible to modify the results after the 2nd examination has been carried out. Another midwife (midwife 'B') will examine with the echOpen probe (blind to the first midwife's result). The alternation between midwife 'A' and midwife 'B' will also be random.

Study Groups

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Pregnant women benefitting ultrasound examination

This is the unique arm of the study. This arm is made of eligible pregnant women, with a pregnancy of at least 37 weeks.

Group Type EXPERIMENTAL

echOpen O1 Handheld Ultrasound device

Intervention Type DEVICE

The performance of the Handheld ultrasound device (echOpen O1 device) will be assessed during these visits for all evaluation criteria.

* One examination with the US machine by the midwife focused on 4 targets ;
* One examination with a classic US machine by the same midwife (comparator) including the search for the four targets ;
* One examination with the US machine by a second operator ; Review of the images obtained by the US machine by the referring radiologist at a separate point of time.

The mode of delivery and the vital status of the mother and newborn will also be collected.

Operator A will start by using either the echOpen O1 device or the US machine (random order, via sealed envelopes) and will then perform the other type of examination.

Another operator (Operator B) will come to perform an examination with the Handheld ultrasound device (blind to the result of the first operator).

The switch between operators A and B will also be random.

Interventions

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echOpen O1 Handheld Ultrasound device

The performance of the Handheld ultrasound device (echOpen O1 device) will be assessed during these visits for all evaluation criteria.

* One examination with the US machine by the midwife focused on 4 targets ;
* One examination with a classic US machine by the same midwife (comparator) including the search for the four targets ;
* One examination with the US machine by a second operator ; Review of the images obtained by the US machine by the referring radiologist at a separate point of time.

The mode of delivery and the vital status of the mother and newborn will also be collected.

Operator A will start by using either the echOpen O1 device or the US machine (random order, via sealed envelopes) and will then perform the other type of examination.

Another operator (Operator B) will come to perform an examination with the Handheld ultrasound device (blind to the result of the first operator).

The switch between operators A and B will also be random.

Intervention Type DEVICE

Other Intervention Names

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Multicentric prospective comparative study

Eligibility Criteria

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Inclusion Criteria

* Pregnancy ≥ 37 weeks of amenorrhea
* Women aged ≥ 18 years old
* Delivery scheduled to take place in the recruitment center
* Have given her written informed consent to participate

Exclusion Criteria

* Known fetal morphological abnormality
* Emergency context during the participant's management
* Obstetrical work in progress
* Women anticipating displacement or no delivery at the clinical site
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Institut Pasteur de Dakar

OTHER

Sponsor Role collaborator

Fondation Sanofi Espoir

UNKNOWN

Sponsor Role collaborator

echOpen Factory

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Fatoumata D. Sarr, M.D., MPH

Role: PRINCIPAL_INVESTIGATOR

Institut Pasteur de Dakar

Locations

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Poste de Santé de Karang

Karang, Fatick, Senegal

Site Status

Centre de Santé de Sokone

Sokone, Fatick, Senegal

Site Status

Countries

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Senegal

References

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Related Links

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https://www.who.int/publications-detail-redirect/9789241549912

WHO recommendations on antenatal care for a positive pregnancy experience

Other Identifiers

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2023-P01

Identifier Type: -

Identifier Source: org_study_id

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