Efficacy and Safety of Autologous Cryopreserved Platelets in Patients With PTR
NCT ID: NCT05761457
Last Updated: 2023-03-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
25 participants
INTERVENTIONAL
2023-03-01
2025-01-10
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Treatment group
Patients receive cryopreserved autologous platelet transfusion
Cryopreserved autologous platelet transfusion
Autologous PLTs were collected and transfused as an individualized treatment approach, when the platelet is less than 20\*10E9/L or severe bleeding occurred.
Interventions
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Cryopreserved autologous platelet transfusion
Autologous PLTs were collected and transfused as an individualized treatment approach, when the platelet is less than 20\*10E9/L or severe bleeding occurred.
Eligibility Criteria
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Inclusion Criteria
* The platelet level \>150\*10E9/L when considering autologous PLT collection
* Age less than 70 years
* The expected life more than 3 months
* Agree to receive autologous platelet cryopreservation and infusion treatment, and sign the informed consent form
Exclusion Criteria
* Patients with bacteremia or sepsis
* Coagulation function abnormality
* Patients who have a history of thrombosis and are receiving anticoagulant treatment
* Severe bleeding within 2 weeks
* Participate in another clinical study within 1 month, and have treatment with potential impact on platelets
* Patients with mental disease
15 Years
70 Years
ALL
No
Sponsors
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The First Affiliated Hospital of Soochow University
OTHER
Responsible Party
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Principal Investigators
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Yue Han, PhD,MD
Role: PRINCIPAL_INVESTIGATOR
First Affiliated Hospital of Soochow University
Locations
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First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China
Countries
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Central Contacts
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Facility Contacts
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References
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Cid J. Autologous cryopreserved platelets to overcome immune platelet refractoriness. Transfusion. 2016 Oct;56(10):2403-2404. doi: 10.1111/trf.13758. No abstract available.
Funke I, Wiesneth M, Koerner K, Cardoso M, Seifried E, Kubanek B, Heimpel H. Autologous platelet transfusion in alloimmunized patients with acute leukemia. Ann Hematol. 1995 Oct;71(4):169-73. doi: 10.1007/BF01910313.
Schiffer CA, Aisner J, Wiernik PH. Frozen autologous platelet transfusion for patients with leukemia. N Engl J Med. 1978 Jul 6;299(1):7-12. doi: 10.1056/NEJM197807062990102.
Other Identifiers
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20221108091732885
Identifier Type: -
Identifier Source: org_study_id
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