V-A ECMO AUTO Mode Registry

NCT ID: NCT05759377

Last Updated: 2025-07-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

46 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-10-11

Study Completion Date

2025-06-03

Brief Summary

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Abiomed Impella V-A ECMO AUTO Mode - Observational Study

Detailed Description

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The overall objective of this study is to collect data during routine Impella usage in an ECpella setting to analyze and assess potential clinical effects, usability, and ease of use of an automated Impella mode to run in conjunction with a VA ECMO system for continued assessment and development of the underlying algorithms in different clinical settings.

The primary objective is thus the collection of clinical events to serve as a database for an in-silico post-hoc analysis of the V-A ECMO AUTO Mode algorithm for the Impella pump. This is accompanied by a secondary objective assessing usability, confirming the user friendliness and ease of use by collection of user experience and insights through a questionnaire and data on alarms and manual user interaction with the AIC out of the operational console data.

Conditions

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Heart Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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V-A ECMO AUTO Mode algorithm

The clinical effects of utilizing the V-A ECMO AUTO Mode in parallel with VA ECMO treatment shall be assessed in different clinical settings. For this, a set of relevant clinical situations and findings ("events") has been defined as trigger points where technical (via AIC) and clinical data shall be collected, linked, and analyzed. This assessment of raw data is important to further develop and adapt the software.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients with ongoing or planned ECpella therapy

Exclusion Criteria

* Age \< 18 years
* Treatment with other than VA ECMO setup
* Treatment with Impella CP® heart pump only
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abiomed Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alexander Kersten, MD

Role: PRINCIPAL_INVESTIGATOR

Uniklinik RWTH Aachen

Locations

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Uniklinik RWTH Aachen

Aachen, North Rhine-Westphalia, Germany

Site Status

HDZ NRW

Bad Oeynhausen, North Rhine-Westphalia, Germany

Site Status

Herzzentrum Dresden GmbH

Dresden, Saxony, Germany

Site Status

Universitäres Herz- und Gefäßzentrum Hamburg

Hamburg, , Germany

Site Status

UKGM Universtitätsklinikum Marburg

Marburg, , Germany

Site Status

Krankenhaus der Barmherzigen Brüder - Herzzentrum Trier

Trier, , Germany

Site Status

Countries

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Germany

Other Identifiers

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2022-R02

Identifier Type: -

Identifier Source: org_study_id

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