Myopia Control Combined PBM With Myopic Defocus Lens in Children

NCT ID: NCT05756959

Last Updated: 2023-03-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

304 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-12-12

Study Completion Date

2027-12-31

Brief Summary

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To study the efficacy of myopi control with two methods: low lever red light and peripheral defocus spectacles with four groups and design with prospective, double-blind, randimized, and with control for 6 month.

Detailed Description

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myopic children with age from 6 \~13 years old. And refraction from -0.50D\~-5.50D.

The red light is low lever laser therapy at wavelength of 650nm.

Conditions

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Myopia, Progressive

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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PBM therapy + SVS

Low lever red light therapy with single vision spectacles

Group Type EXPERIMENTAL

PBM

Intervention Type DEVICE

PBM, is a low intensity red light at wavelength of 650nm; Peripheral defocus spectacels is a peripheral design glasseses for correct myopia and control myopia

Single vision spectacles

Intervention Type DEVICE

Distance vision correction with the single vision spectacles for the myopia correction methods (glasseses for myopia correction)

Peripheral defocus spectacles

a spectacles with special design with peripheral myopic defocus to control myopia progression

Group Type EXPERIMENTAL

Peripheral defocus spectacles

Intervention Type DEVICE

plus power design of many peripheral small lenses to achieve myopic defocus of the retina in the peripheral retina

PBM +Peripheral defocus spectacles

Low lever red light therapy with a spectacles with special design with peripheral myopic defocus to control myopia progression

Group Type EXPERIMENTAL

PBM

Intervention Type DEVICE

PBM, is a low intensity red light at wavelength of 650nm; Peripheral defocus spectacels is a peripheral design glasseses for correct myopia and control myopia

Peripheral defocus spectacles

Intervention Type DEVICE

plus power design of many peripheral small lenses to achieve myopic defocus of the retina in the peripheral retina

Control

single vision spectacles only as the control

Group Type PLACEBO_COMPARATOR

Single vision spectacles

Intervention Type DEVICE

Distance vision correction with the single vision spectacles for the myopia correction methods (glasseses for myopia correction)

Interventions

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PBM

PBM, is a low intensity red light at wavelength of 650nm; Peripheral defocus spectacels is a peripheral design glasseses for correct myopia and control myopia

Intervention Type DEVICE

Peripheral defocus spectacles

plus power design of many peripheral small lenses to achieve myopic defocus of the retina in the peripheral retina

Intervention Type DEVICE

Single vision spectacles

Distance vision correction with the single vision spectacles for the myopia correction methods (glasseses for myopia correction)

Intervention Type DEVICE

Other Intervention Names

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Low lever light therapy; low intensity red light therapy; low lever laser therapy; repeated red light therapy Myopic defocus spectacles for myopia control single vision glasseses for myopia correction lenses

Eligibility Criteria

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Inclusion Criteria

* Informed consent by the supervision of the children
* 6\~13 years old (including both the 6 and 13)
* SE range: -0.50\~-5.50D
* Astigmatism \<=2.00D
* BCVA \>=0.8
* Anisometropia \<=1.50D
* Confirmed to no use of other myopia control intervention

Exclusion Criteria

* Ocular lesions to effect vision or diseases (such as cataract, glaucoma, marcular pathology, cornea lesions, uveitis, retina detachment, congential opitc abnormal and etc.)
* Halo, glare, toutic, ADHD, psoriasis
* Systom disease: immune disease, central nerve system, Down syndrome, asthma, severe cardiopulmonary abnormal, severe liver and renal dysfunction.
* Squint, ocular lesion or acute imflammation.
* Other myopia control interventions within recent 3 month such as atropine, device, orthokeratology, multi-focus soft lens, multi-function spectacles.
Minimum Eligible Age

6 Years

Maximum Eligible Age

13 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The First People's Hospital of Xuzhou

OTHER

Sponsor Role collaborator

Beijing Airdoc Technology Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yan Wang, BA

Role: STUDY_DIRECTOR

The First People's Hospital of Xuzhou

Locations

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the first people's hospital of Xuzhou

Xuzhou, Jiangsu, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Ying Li, MD, PHD

Role: CONTACT

+8615162130727

Lei Qiao, PHD, MD

Role: CONTACT

+15162127602

Facility Contacts

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Ying Li, MD.Ph.D.

Role: primary

+8615162130727

Other Identifiers

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Xuzhou First People's Hospital

Identifier Type: -

Identifier Source: org_study_id

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