A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.
NCT ID: NCT05751304
Last Updated: 2023-03-02
Study Results
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Basic Information
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UNKNOWN
NA
100 participants
INTERVENTIONAL
2023-03-01
2024-02-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Group D
(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 5μg dexametomidine.
Dexmedetomidine
(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 5μg Dexametomidine.
Group K
(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 0.1 mg/kg ketamine.
Ketamine
(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 0.1 mg/kg ketamine.
Interventions
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Dexmedetomidine
(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 5μg Dexametomidine.
Ketamine
(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 0.1 mg/kg ketamine.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Drug abuse.
* Patient with neurological, psychiatric or neuromuscular disease.
* Chronic pain on medicine.
* Known allergy to the study medications.
* Patients e contraindications to intrathecal anesthesia .
18 Years
50 Years
ALL
Yes
Sponsors
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Sohag University
OTHER
Responsible Party
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Ziad Ahmed Ali
A comparative study between intrathecal dexmedetomidine VS ketamine with intrathecal bupivacaine in orthopedic lower limb surgeries.
Locations
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Sohag University Hospital
Sohag, , Egypt
Countries
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Central Contacts
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Ahmed E Abd Elrahman, Professor
Role: CONTACT
Facility Contacts
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Magdy M Amin, Professor
Role: primary
References
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American Society of Anesthesiologists Task Force on Acute Pain Management. Practice guidelines for acute pain management in the perioperative setting: an updated report by the American Society of Anesthesiologists Task Force on Acute Pain Management. Anesthesiology. 2012 Feb;116(2):248-73. doi: 10.1097/ALN.0b013e31823c1030. No abstract available.
Kehlet H, Jensen TS, Woolf CJ. Persistent postsurgical pain: risk factors and prevention. Lancet. 2006 May 13;367(9522):1618-25. doi: 10.1016/S0140-6736(06)68700-X.
Kehlet H, Holte K. Effect of postoperative analgesia on surgical outcome. Br J Anaesth. 2001 Jul;87(1):62-72. doi: 10.1093/bja/87.1.62. No abstract available.
Brennan F, Carr DB, Cousins M. Pain management: a fundamental human right. Anesth Analg. 2007 Jul;105(1):205-21. doi: 10.1213/01.ane.0000268145.52345.55.
Other Identifiers
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Soh-Med-23-02-09
Identifier Type: -
Identifier Source: org_study_id
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