Cardiovascular Risk Categories and Attaining LDL-C Targets in Middle Eastern Adults Aged 30-55 Years of Age

NCT ID: NCT05745272

Last Updated: 2024-01-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-12-11

Study Completion Date

2023-12-24

Brief Summary

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Individuals evaluated for primary and secondary cardiovascular prevention have different levels of cardiovascular risk These levels of risk are the main determinants of the low-density lipoprotein cholesterol (LDL-C) target blood levels that need to be attained.

Detailed Description

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Individuals evaluated for primary and secondary cardiovascular prevention fall into different levels of cardiovascular risk according to their clinical profile of having atherosclerotic cardiovascular disease (ASCVD), risk factors, and their SCORE. These levels of risk are the main determinants of the low-density lipoprotein cholesterol (LDL-C) target blood levels that need to be attained using LDL-C-lowering agents (LLA).

Contemporary studies that evaluated levels of cardiovascular risk and LDL-C goal attainment in the Middle East are scarce. A prior study (CEPHEUS LEVANT) in the Middle East demonstrated that about 1 in 4 high-risk patients reach LDL-C goals.

The current study aims at studying cardiovascular risk categories according to the 2019 ESC/EAS and 2018 ACC/AHA Guidelines, and the attainment of LDL-C treatment goals in consecutive individuals aged 18-55 years who are evaluated in tertiary care centers as inpatients or in ambulatory care settings. The above age bracket was chosen because these are the individuals most prone to acute cardiovascular events with a high prevalence of diabetes mellitus and cigarette smoking.

Conditions

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Atherosclerotic Cardiovascular Risk Low-density-lipoprotein (LDL) Cholesterol

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* Age 18-55 y
* Individuals can give a history of the presence or absence of ASCVD and its risk factors

Exclusion Criteria

* Age below 18 or older than 55
* Refusal of inability to give history on ASCVD and its risk factors
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Cardiovascular Academy Group of the JCS

UNKNOWN

Sponsor Role collaborator

The Jordan Cardiac Society (JCS)

UNKNOWN

Sponsor Role collaborator

Istishari Hospital Department of Clinical Research

UNKNOWN

Sponsor Role collaborator

Jordan Collaborating Cardiology Group

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Imad A. Alhaddad, MD FACC

Role: STUDY_CHAIR

Department of Cardiology, Jordan Hospital, Amman, Jordan

Ramzi Tabbalat

Role: STUDY_DIRECTOR

Cardiology Department, Abdali Hospital

Ayman Hammoudeh, MD FACC

Role: PRINCIPAL_INVESTIGATOR

Department of Clinical Research, Istishari Hospital, Aman, Jordan

Locations

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Istishari Hospital

Amman, , Jordan

Site Status

Countries

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Jordan

Other Identifiers

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CVA-G/JCS-1/2023

Identifier Type: -

Identifier Source: org_study_id

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