Modified Rekovelle and Menopur Combination Protocol to Avoid Monitoring Before Day 10 of Stimulation

NCT ID: NCT05737979

Last Updated: 2024-02-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

772 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-27

Study Completion Date

2024-01-27

Brief Summary

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Follitropin delta (Rekovelle) algorithm established by Ferring provides personalized gonadotrophin doses based on each patient's weight and AMH. As a result, risks of stimulation failure or ovarian hyperstimulation syndrome (OHSS) during an in vitro fertilization (IVF) cycle are minimized.

As a standard practice for OHSS prevention at clinique ovo, women undergoing IVF will have a scheduled ultrasound and blood test on the sixth day of their stimulation treatment. However, with the determination of the Rekovelle and Menopur algorithm, the risks of OHSS before the tenth day have been considerably minimized.

Detailed Description

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The purpose of this study is to evaluate the necessity of programming an ultrasound and blood test prior to the tenth day of ovarian stimulation when women are on personalized doses of Rekovelle and Menopur duting an antagonist IVF cycle. Based on the results of the analysis, we will assess the economic impact that programming an ultrasound and blood test at day 10 might have.

Conditions

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Infertility IVF

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Women undergoing IVF

Women undergoing an antagonist in vitro fertilization cycle using Rekovelle and Menopur for stimulation

Study chart review

Intervention Type OTHER

Evaluation of the IVF cycle using the prescribed medication

Interventions

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Study chart review

Evaluation of the IVF cycle using the prescribed medication

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Women of 18 years of age or older having provided consent to chart access for scientific publication in the IVF consent form
* Antagonist IVF cycle using combination of Rekovelle and Menopur for stimulation according to the modified protocol employed at clinique ovo without deviation
* Presence of both ovaries

Exclusion Criteria

* Second cycle of Duo-Stim IVF
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Clinique Ovo

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jacques Kadoch, MD

Role: PRINCIPAL_INVESTIGATOR

Clinique Ovo

Locations

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Clinique Ovo

Montreal, Quebec, Canada

Site Status

Countries

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Canada

Other Identifiers

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3189

Identifier Type: -

Identifier Source: org_study_id

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