Study to Assess the Design of Use of REKOVELLE® in Women Undergoing In Vitro Fertilisation or Intracytoplasmic Sperm Injection Procedures in Routine Clinical Practice

NCT ID: NCT04503707

Last Updated: 2021-12-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-17

Study Completion Date

2021-10-31

Brief Summary

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The aim of the study is to explore how the individualized dosing regimen of REKOVELLE is used in routine clinical practice and to describe the effectiveness and safety of REKOVELLE under real-world conditions.

Detailed Description

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Conditions

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Controlled Ovarian Stimulation

Keywords

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Follicle Stimulating Hormone (FSH) Assisted Reproductive Technologies (ART) Follitropin Delta REKOVELLE

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Follitropin Delta

Treatment according to routine clinical practice.

Follitropin Delta

Intervention Type DRUG

The Intervention (solution for injection) is delivered with a pre-filled injection pen. The REKOVELLE dose will be based on a recent determination (within the last 12 months) of AMH (anti- müllerian hormone) measured by the ELECSYS AMH Plus Immunoassay.

Interventions

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Follitropin Delta

The Intervention (solution for injection) is delivered with a pre-filled injection pen. The REKOVELLE dose will be based on a recent determination (within the last 12 months) of AMH (anti- müllerian hormone) measured by the ELECSYS AMH Plus Immunoassay.

Intervention Type DRUG

Other Intervention Names

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REKOVELLE

Eligibility Criteria

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Inclusion Criteria

* Females aged 18 years or older at enrolment
* Who are treated for IVF or ICSI treatment cycle using fresh or frozen ejaculated sperm from male partner or sperm donor
* Who are prescribed REKOVELLE for the first time and using the dosing algorithm to define the dose regimen: a previous cycle with REKOVELLE should not be allowed
* Who have been informed verbally and in writing about this study content and who do not object to their data being electronically processed.

Exclusion Criteria

* Participating in an interventional clinical trial in which any treatment or follow-up is mandated
* Women with a contraindication for prescription of REKOVELLE treatment
* Oocyte donors
* Women undergoing ovarian stimulation for fertility preservation
* Women undergoing their third or fourth attempt of IVF or ICSI for the current parental project.
* Subject non-affiliated to French Social Security
* Women placed under judicial protection, guardianship, or supervision
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Ferring Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Global Clinical Compliance

Role: STUDY_DIRECTOR

Ferring Pharmaceuticals

Locations

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Hôpital Pellegrin

Bordeaux, , France

Site Status

Hôpital Femme Mère Enfant

Bron, , France

Site Status

Hopital Antoine Béclère

Clamart, , France

Site Status

Centre Hospitalier Intercommunal de Créteil

Créteil, , France

Site Status

Centre hospitalier de Lille-Hopital de Flandre

Lille, , France

Site Status

Institut de Médecine de la Reproduction (there may be other sites in this country)

Marseille, , France

Site Status

CHU Montpellier

Montpellier, , France

Site Status

CHU Nantes Hôpital Hôtel Dieu

Nantes, , France

Site Status

Maternité Port Royal

Paris, , France

Site Status

Centre Hospitalier Intercommunal de Poissy

Poissy, , France

Site Status

Clinique Mutualiste La Sagesse

Rennes, , France

Site Status

Pierre OGER

Rueil-Malmaison, , France

Site Status

CMCO

Strasbourg, , France

Site Status

CHU Toulouse - Hôpital Paule de Viguier

Toulouse, , France

Site Status

Countries

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France

Other Identifiers

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000370

Identifier Type: -

Identifier Source: org_study_id