Electrocardiograph Changes and Holter Abnormalities in Children With Predialytic Chronic Kidney Disease

NCT ID: NCT05726071

Last Updated: 2023-02-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-11-01

Study Completion Date

2023-10-01

Brief Summary

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CKD is a strong risk factor for cardiovascular disease and mortality , As in adults, cardiovascular disease occurs in some children with CKD before they reach ESRD as well as after

Detailed Description

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This work aims to study the electrophysiological changes in cardiovascular system in children with predialytic CKD. ECG is important in detection of cardiac rhythm abnormalities, cardiac conduction defects and detection of myocardial ischemia

Conditions

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Predialytic Chronic Kidney Disease

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Holter

24 hour electrocardiography

Intervention Type DEVICE

Other Intervention Names

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ECG Fukuda Denshi CardiMax ECG device model FCP-7101

Eligibility Criteria

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Inclusion Criteria

Age 1 to 15 year children with predialytic chronic kidney disease GFR.\>15 ml\\min per 1.73m2 , stages 1, 2, 3, 4 according to (KDOQI stages).

Exclusion Criteria

* Age \>15 year On regular dialysis GFR\<15 ml\\min per 1.73m2, Stage 5 according to (KDOQI stages). Children with known cardiovascular disease or known arrhythmia Patients on the potential medication affecting ECG result as B-blocker, antipsychotics , antidepressant
Minimum Eligible Age

1 Year

Maximum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Wethab Khaled Mohamed

Pediatric resident at El Helal Hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sohag faculty of medicine

Sohag, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Wethab K Mohamed, Pediatric resident

Role: CONTACT

+2001090090162

Shaimaa M Mahmoud, Assistant professor

Role: CONTACT

Facility Contacts

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Magdy M Amin, professor

Role: primary

(093)- 4602963

References

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Shafi S, Saleem M, Anjum R, Abdullah W, Shafi T. ECG Abnormalities In Patients With Chronic Kidney Disease. J Ayub Med Coll Abbottabad. 2017 Jan-Mar;29(1):61-64.

Reference Type BACKGROUND
PMID: 28712176 (View on PubMed)

Park S, Yum Y, Cha JJ, Joo HJ, Park JH, Hong SJ, Yu CW, Lim DS. Prevalence and Clinical Impact of Electrocardiographic Abnormalities in Patients with Chronic Kidney Disease. J Clin Med. 2022 Sep 15;11(18):5414. doi: 10.3390/jcm11185414.

Reference Type BACKGROUND
PMID: 36143060 (View on PubMed)

Chavers BM, Herzog CA. The spectrum of cardiovascular disease in children with predialysis chronic kidney disease. Adv Chronic Kidney Dis. 2004 Jul;11(3):319-27. doi: 10.1053/j.arrt.2004.04.002.

Reference Type BACKGROUND
PMID: 15241746 (View on PubMed)

Other Identifiers

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Soh-med-23-01-12

Identifier Type: -

Identifier Source: org_study_id

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