Frailty, Cognitive Function and Health-related Quality of Life in Older Adults With Advanced Chronic Kidney Disease.

NCT ID: NCT05705011

Last Updated: 2024-02-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

240 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-03-01

Study Completion Date

2023-03-12

Brief Summary

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This observational study explores the impact of cognitive impairment and frailty in older adults with advanced chronic kidney disease \].

The main question\[s\] it aims to answer are:

* What determines the time to initiate dialysis? Cognitive impairment or frailty?
* What does predict the time to death? Presence of frailty or cognitive impairment?
* What does correlate strongly with time-low health-related quality of life? frailty or cognitive impairment?

Detailed Description

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Conditions

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CKD Stage 4 CKD Stage 5 Frailty Cognitive Impairment

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients age 65 years or older.
* CKD stage 4 and 5 who were identified by two consecutive measurements of estimated glomerular filtration rate (eGFR) \<30 mL/min/1.73 m2 separated by more than 3 months.

Exclusion Criteria

* Patients younger than 65 years old.
* Chronic kidney disease stages 1,2, and 3.
* Dialysis dependence
* History of kidney transplantation.
* Initial visit with the health care provider.
* Recent acute kidney injury.
* Patients who had been hospitalized for more than 2 months before the visit (because long hospitalization might affect the degree of frailty)
* Patients with myocardial infarction and cerebrovascular accident 3 months before the assessment
* Patients who are blind or with limb amputation.
* Patients who refuse to participate.
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Grigore T. Popa University of Medicine and Pharmacy

OTHER

Sponsor Role lead

Responsible Party

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Hani Hussien

Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hani Hussien, MD

Role: PRINCIPAL_INVESTIGATOR

University of Medicine and Pharmacy "Grigore T. Popa" - Iași

Locations

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University of Medicine and Pharmacy "Grigore T. Popa"

Iași, , Romania

Site Status

Countries

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Romania

Other Identifiers

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Nephrogeriatrics

Identifier Type: -

Identifier Source: org_study_id

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