MedDataX Logo

Surgical and Non Surgical Treatment Option in Poly Cystic Ovary Cases

NCT ID: NCT05699356

Last Updated: 2023-01-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-10-11

Study Completion Date

2023-03-28

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The study will focus on treatment of Poly Cystic Ovary Syndrome patients with infertility The aim is to to find the best treatment by comparison of surgical and non surgical intervention

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

IVF\ICSI Outcome in Women With Polycystic Ovary Syndrome

NCT05756023

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
RECRUITING NA

Anxiety and Sexual Malfunction Functions in Infertile Pcos Women

NCT05056272

Quality of Life
COMPLETED

Sexual Dysfunction in Infertile Women With PCOS Undergoing Fertility Treatment

NCT05402800

Sexual Dysfunction PCOS
UNKNOWN

Health-related Quality of Life of Women with Polycystic Ovary Syndrome At Sohag University Hospital

NCT06832735

Polycystic Ovary Syndrome (PCOS) Women
NOT_YET_RECRUITING

Correlation of Insulin Resistance With Hormonal and Ovarian Morphological Characteristics in Patients With Polycystic Ovarian Syndrome

NCT05661565

Study the Relationship Between Insulin Resistance With Hormonal and Ovarian Morphological Characteristics in Patients With Polycystic Ovarian Syndrome
UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

INTRODUCTION Infertility is the failure of couples to conceive after one year of having regular unprotected coitus 1, 2\&3 Globally there are 48 -186 million people cases reported with infertility. The common causes of infertility are being male factor, tubal peritoneal factor, cervical mucus, an ovulatory disorders and others causes including anti-sperm antibodies, luteal phase deficiency, diabetic mellitus, genital tract infection 1,2\&4 Infertility is often multifactorial so during treatment multiple investigations should be conducted 2 Anovulation cover 30% of all infertility cases, is a complex process by which there is a failure of ovary to release mature ovarian follicles and involves a lot of potential causes 2\&5 The clinical symptoms of anovulating cycles are irregular periods, light or heavy menses, deficiency of cervical mucus, Irregular Basal Body Temperature (BBT) 2\&5 The common causes of anovulatory cycle is Polycystic Ovarian Syndrome (PCOS), other causes are due to hypothalamus or pituitary gland dysfunction, Premature ovarian failure, high serum estradiol in follicular phase, age above 45, hyper prolactinemia, subclinical hypothyroidism, drugs, luteinized unruptured follicles, Diabetes mellitus, athletic activity and people who do not eat and become very slim 1,2\&5 Polycystic Ovarian Syndrome (PCOS) is a condition in a female of child bearing age characterized by menstrual disorders, hyperandrogenism, multiple ovarian cysts and anovulatory cycle 6 The causes of this condition are idiopathic, but the following reasons are highly suggested to be associated with PCO 6\&7 Insulin resistance develop from excess insulin lead the body to produce more androgen and causing anovulatory cycle 6 women with PCOS have low grade inflammation that stimulates Poly cystic ovaries to produce androgen which can lead changes in blood vessels and heart 6 PCOS also may be due familiar susceptibility 6 The sign and symptoms of PCO are Menstrual disorders including missed period more than 35 days, infrequent period less 9 menses in a year, irregular menses light or heavy period 6\&7 Hyperandrogenism manifestation like hirsutism, clitoromegaly, masculinization, severe acne, in severe form of PCO (hyperthecosis) there is deepening of voice 6, 7\&8 History of infertility due to intermittently ovulation, the condition also is associate with higher chance of miscarriage 8 Polycystic ovaries presence of numerous small cysts filled with fluid in the ovaries 6\&7 Majority of PCO patients are obese which worsen the symptoms of PCO 6\&8 About 10 % of PCO cases have type 2 Diabetic Mellitus and 30-40 % at age of 40 have impaired glucose tolerance test 8 Sleep apnea which predispose PCO affected patients to cardiovascular disease 8 COMPLICATION OF PCO Infertility, gestational diabetes, Pregnancy induce hypertension, abortion or pre term birth, steatohepatitis, cardiovascular disease, Type 2 diabetes or prediabetes, lack of sleep, depression, thinning of hair, anxiety and eating disorder, abnormal uterine bleeding, acanthosis nigricans, armpit and under breasts, endometrial cancer a1 a2 The treatment of PCO is widely including life style modification, drug treatment, FDA safety alerts, metabolic derangements, anovulation, hirsutism, diet and activity, surgical intervention a3

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Poly Cystic Ovary Treatment for Infertility

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Surgical treatment of Poly cystic ovary for infertility by laparoscopic drilling

laparoscopic drilling response in Poly Cystic Ovary case

laparoscopic drilling

Intervention Type PROCEDURE

Surgical intervension

Non-surgical treatment of Poly cystic ovary for infertility

induction,Anti estrogen,Insulin sensitizing agent, Aromatase Inhibitor,Gonadotropin

Non Surgical treatment

Intervention Type OTHER

Non Surgical

Treatment of Poly cystic ovary for infertility by Life style modification

Life style modification response in Poly Cystic Ovary case for treatment of infertility

Treatment of Poly cystic ovary for infertility by Life style modification

Intervention Type BEHAVIORAL

Non Surgical

Treatment of Poly cystic ovary for infertility by Assisted reproductive technique

Assisted reproductive technique response in Poly Cystic Ovary case for treatment of infertility

Treatment of Poly cystic ovary for infertility by Assisted reproductive technique

Intervention Type PROCEDURE

Surgical intervention

Treatment of Poly cystic ovary for infertility by controlling menstrual disorders

Controlling menstrual disorders response in Poly Cystic Ovary case for treatment of infertility

Non Surgical treatment

Intervention Type OTHER

Non Surgical

Treatment of Poly cystic ovary for infertility by Cutaneous manifestation

Cutaneous manifestation response in Poly Cystic Ovary case for treatment of infertility

Non Surgical treatment

Intervention Type OTHER

Non Surgical

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Non Surgical treatment

Non Surgical

Intervention Type OTHER

laparoscopic drilling

Surgical intervension

Intervention Type PROCEDURE

Treatment of Poly cystic ovary for infertility by Life style modification

Non Surgical

Intervention Type BEHAVIORAL

Treatment of Poly cystic ovary for infertility by Assisted reproductive technique

Surgical intervention

Intervention Type PROCEDURE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Induction, Aromatase inhibitor,Insulin sensitizing agent,Gonadotropin,Anti estrogen Non surgical treatment option Surgical treatment option

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Infertility cases with Poly Cystic Ovary sundrome

Exclusion Criteria

* Infertility cases not related with Poly cystic ovary
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Sohag University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Hawala Saleh Mohammed

Resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Suhag University hospital

Sohag, , Egypt

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Hawala S Mohammed, Resident

Role: CONTACT

[email protected]
+201104354205

Yasser A Helmy, Professor

Role: CONTACT

[email protected]
+201226102105

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Magdi M Amini, Professor

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Soh-Med-22-10-03

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

The Study of Polycystic Ovary Syndrome (PCOS) and Questionnaire
NCT01256970 COMPLETED
The Study of Polycystic Ovary Syndrome(PCOS) With Gene and Questionnaire
NCT01114659 COMPLETED
The Effect of Polycystic Ovary Syndrome on the Embryo Morphokinetics ( PCOS )
NCT05438355 COMPLETED
Role of Nesfatin-1 and Nicotinamide in Infertile Women With Polycystic Ovary Syndrome
NCT03870035 UNKNOWN
Ovarian Innervation Study in Patients With Polycystic Ovary Syndrome (PCOS)
NCT05966571 UNKNOWN
Microbiome and Polycystic Ovaries
NCT04836910 NOT_YET_RECRUITING
The Role of Autoimmunity and Obesity in Polycystic Ovary Syndrome
NCT05929950 UNKNOWN
Effects of Alpha-acid Lipoic in PCOS Women
NCT02666170 UNKNOWN NA
The Effects of the Mediterranean Diet and Synbiotics in Polycystic Ovary Syndrome
NCT07342946 NOT_YET_RECRUITING NA
The Efficacy of Progestins in Treatment of Functional Ovarian Cyst
NCT03456570 UNKNOWN EARLY_PHASE1
Clinical Efficacy and Safety of Laparoscopic Sleeve Gastrectomy in Obese Patients With PCOS
NCT05536583 COMPLETED NA
Gut Microbiome in Patients With Polycystic Ovary Syndrome
NCT02078505 UNKNOWN NA
Treat of Functional Ovarian Cysts by Compare Between Cocs and Progesterone Only Pills
NCT05244811 UNKNOWN PHASE3
Novel Subtypes of Polycystic Ovary Syndrome
NCT06124391 RECRUITING
Multidisciplinary Diagnosis and Treatment of Polycystic Ovary Syndrome
NCT06047574 RECRUITING
The Psychological and Social Impact of PCOS
NCT05982236 UNKNOWN
Comparison Between Laparoscopic Ovarian Diathermy and Clomiphene Citrate in Women With Anovulatory PCOS
NCT00220545 COMPLETED NA
Assessment of the Impact of Polycystic Ovary Syndrome on Women's Sexuality
NCT06887296 COMPLETED
Health Risks and Barriers to Management Across the PCOS Lifespan
NCT05769426 COMPLETED
Study of Mechanisms of Anovulation in Polycystic Ovary Syndrome
NCT00492882 COMPLETED
Anti-Mullerian Hormone as Predictor of Ovarian Responce to Clomiphene Citrate in PCOS
NCT03316469 UNKNOWN NA
Awareness Of Gynecologists About Role Of Physical Therapy In Management Of Polycystic Ovarian Syndrome
NCT06543225 COMPLETED
Serum Ghrelin in Polycystic Ovary Syndrome
NCT02087410 UNKNOWN
The Effect of Polycystic Ovary Syndrome Phenotypes on Quality of Life and Sexual Function
NCT06428786 COMPLETED
Ovary Syndrome for Efficient Diagnosis and Targeted Therapy
NCT06102629 NOT_YET_RECRUITING NA