COVID-19 Infection and Idiopathic Membranous Nephropathy

NCT ID: NCT05691179

Last Updated: 2023-02-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

130 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-10

Study Completion Date

2023-05-31

Brief Summary

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Infection is one of common risk factors for relapsing of idiopathic membranous nephropathy (IMN). However, it is still unclear wheather COVID-19 infection can induce the relapsing of IMN. Herein, in this prospective, multi-center, cohort study, the investigator enrolled the IMN patients with COVID-19 infection.

All subjects will be followed for three months with four visits at 1, 2 and 3 months. Then the investigator will compare the rate of replase of IMN in the two groups to evaluate the association of COVID-19 infection and replapse of IMN.

Detailed Description

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Conditions

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Idiopathic Membranous Nephropathy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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COVID-19 infection group

the patients with IMN and COVID-19 infection

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. the status of nephrotic syndrome is complete remmision or partial remmision;
2. estimated glomerular filtration rate (eGFR according to the CKD-EPI formula) ≥60 mL/min per 1.73 m2;
3. patients with a moderate risk of IMN.

Exclusion Criteria

1. secondary causes of MN;
2. the labarotary data two months before enrolement is absent.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beijing Pinggu District Hospital

OTHER

Sponsor Role collaborator

Beijing Fangshan District Liangxiang Hospital

OTHER

Sponsor Role collaborator

Beijing Friendship Hospital

OTHER

Sponsor Role lead

Responsible Party

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Wenhu Liu

Professor Wenhu Liu

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Beijing Friedship Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Beijing Pinggu Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Beijing Liangxiang Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Zongli Diao, Dr.

Role: CONTACT

86-10-63138579

Facility Contacts

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Wenhu Liu, Doctor

Role: primary

+86-01-63139144

Chaomin Wang, Dr.

Role: primary

86-10-89992020

Chunyu Wang, Dr.

Role: primary

86-10-81356100

Other Identifiers

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2022-P2-429-01

Identifier Type: -

Identifier Source: org_study_id

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