Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LINO-1713 in Healthy Korean Female Subjects

NCT ID: NCT05677035

Last Updated: 2023-01-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-11

Study Completion Date

2022-06-15

Brief Summary

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A single-center, open-label, parallel-group, phase 1 study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of LINO-1713 in healthy Korean female subjects

Detailed Description

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Conditions

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Contraception

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Pharmacokinetic evaluation

LINO-1713 (Estetrol 15mg/Drospirenone 3mg)

Group Type EXPERIMENTAL

LINO-1713 1 tablet

Intervention Type DRUG

LINO-1713 1 tablet is administered once. Oral administration with 200mL of water

Pharmacodynamic evaluation

LINO-1713 (Estetrol 15mg/Drospirenone 3mg)

Group Type EXPERIMENTAL

LINO-1713 once a day for 24 days

Intervention Type DRUG

Oral administration is performed with 200 mL of water. Instruct subjects to take the drug at the same time as possible.

Interventions

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LINO-1713 1 tablet

LINO-1713 1 tablet is administered once. Oral administration with 200mL of water

Intervention Type DRUG

LINO-1713 once a day for 24 days

Oral administration is performed with 200 mL of water. Instruct subjects to take the drug at the same time as possible.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Women with a Body Mass Index (BMI) between 18kg/m2 \~ 28kg/m2

Exclusion Criteria

* Clinically significant cardiovascular disease, respiratory disease
Minimum Eligible Age

19 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Hyundai Pharm

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Korea University Anam Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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HT-014-01

Identifier Type: -

Identifier Source: org_study_id

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