A Post-Market Domestic (US) and International Data Collection to Assess the Truliant Knee System

NCT ID: NCT05653102

Last Updated: 2024-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-23

Study Completion Date

2035-07-31

Brief Summary

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A Post-Market Domestic (US) and International Data Collection to Assess the Truliant® Knee System

Detailed Description

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Patient outcomes data is important for assessing the post-market safety and effectiveness of orthopedic medical devices. The purpose of this study is to collect clinical and patient outcomes and survivorship data for patients who have received or will receive a Truliant® knee prosthesis manufactured or distributed by Exactech Inc (Gainesville, Florida, USA).

Conditions

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Knee Arthroplasty, Total

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Prospective Subjects

Enrolled in the study pre-surgery. Subjects who agree to participate in the study that have not had surgery prior to being enrolled in the study.

Truliant Total Knee System

Intervention Type DEVICE

Total Knee Arthroplasty using Exactech's Truliant® branded components are compatible with Optetrak branded components.

Retrospective to Prospective

Subjects enrolled in the study post- surgery then continue to participate in the study prospectively. Subjects who agree to participate in the study that have undergone surgery prior to enrollment in the study. Data for these subjects will collected from the subject's medical record for the time period prior to enrollment in the study containing data pertaining to the index surgery (retrospective data) and from the patient after they are enrolled in the study during the post-operative time period (prospectively).

Truliant Total Knee System

Intervention Type DEVICE

Total Knee Arthroplasty using Exactech's Truliant® branded components are compatible with Optetrak branded components.

Retrospective Only Subjects

Subjects enrolled in the study post-study surgery with no intent to continue as prospective subjects. Patient's clinical record includes a signed HIPAA waiver allowing for the use of clinical record data for the purpose of clinical research outside of the operating institution.

Truliant Total Knee System

Intervention Type DEVICE

Total Knee Arthroplasty using Exactech's Truliant® branded components are compatible with Optetrak branded components.

Interventions

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Truliant Total Knee System

Total Knee Arthroplasty using Exactech's Truliant® branded components are compatible with Optetrak branded components.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Cohort 1. Prospective / Subjects- Enrolled in the study pre-surgery

1. Subjects who agree to participate in the study that have not had surgery prior to being enrolled in the study.
2. Skeletally mature (18 years of age or older).
3. Subject is willing and able to provide written informed consent for participation in the study.
4. Subject is to receive a Truliant® total knee replacement for Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-Traumatic Arthritis, Polyarthritis, Primary Implantation Failure, or as a Conversion of Uni-Compartmental Knee.
5. The knee replacement will be performed by the investigator or a surgeon sub-investigator.
6. The devices will be used according to the approved indications.

Cohort 2. Retrospective to Prospective / Subjects enrolled in the study post- surgery then continue to participate in the study prospectively.

1. Subjects who agree to participate in the study that have undergone surgery prior to enrollment in the study. Data for these subjects will collected from the subject's medical record for the time period prior to enrollment in the study containing data pertaining to the index surgery (retrospective data) and from the patient after they are enrolled in the study during the post-operative time period (prospectively).
2. Skeletally mature (18 years of age or older).
3. Subject is willing and able to provide written informed consent for participation in the study.
4. Subject received a Truliant® total knee replacement for Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-Traumatic Arthritis, Polyarthritis, Primary Implantation Failure, or as a Conversion of Uni-Compartmental Knee.
5. The knee replacement was performed by the investigator or a surgeon sub-investigator.
6. The devices are/were used according to the approved indications.


o Demographic Data
1. Gender
2. Age at surgery
3. Height/Weight
4. Indication for surgery
5. Prior Injuries/Surgeries on index knee
6. Comorbidities
* Operative:

* Date of Surgery
* Type of Surgery (Primary / Revision)
* All component product information, including catalogue reference numbers
* Adverse Event Information, if applicable

Cohort 3. Retrospective Only Subjects enrolled in the study post-study surgery with no intent to continue as prospective subjects. Note: No prospective data may be collected from a subject if they are enrolled under this cohort unless the subject is willing and able to provide written informed consent for participation in the study.

1. Skeletally mature at the time of the surgery (18 years of age or older).
2. The patient's clinical record includes a signed HIPAA waiver allowing for the use of clinical record data for the purpose of clinical research outside of the operating institution.
3. The patients clinical record includes a documented procedure that includes, or is related to, TKA with a Truliant® Knee system device.
4. The knee replacement was performed by the investigator or a surgeon sub-investigator.
5. The devices are/were used according to the approved indications.

* Pre-Operative:

* Demographic Data
* Gender
* Age at surgery
* Height/Weight
* Indication for surgery
* Prior Injuries/Surgeries on index knee
* Comorbidities
* Operative:

* Date of Surgery
* Type of Surgery (Primary / Revision)
* All component product information, including catalogue reference numbers Adverse Event Information, if applicable

Exclusion Criteria

* Patient was \<18 years of age at time of surgery
* Patient does not meet indicated population for use criteria for this device
* Patient is pregnant
* Patient is a prisoner
* Patient has a physical or mental condition that would invalidate the results
* Patient is contraindicated for the surgery (e.g., metal allergy)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Exactech

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University of Colorado Health

Aurora, Colorado, United States

Site Status RECRUITING

Florida Research Associates

DeLand, Florida, United States

Site Status RECRUITING

Nevada Orthopaedic and Spine Center

Las Vegas, Nevada, United States

Site Status RECRUITING

Crystal Clinic

Akron, Ohio, United States

Site Status RECRUITING

Medical University South Carolina

Charleston, South Carolina, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Pearl Harris

Role: CONTACT

352-327-4846

Alex Knisely

Role: CONTACT

352-377-1140

Facility Contacts

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Frank Somoza

Role: primary

Diane Martin

Role: primary

Ronald Hillock, MD

Role: primary

Ginny Texter

Role: primary

Lisa Mock

Role: primary

References

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Meftah M, White PB, Ranawat AS, Ranawat CS. Long-term results of total knee arthroplasty in young and active patients with posterior stabilized design. Knee. 2016 Mar;23(2):318-21. doi: 10.1016/j.knee.2015.10.008. Epub 2016 Jan 29.

Reference Type RESULT
PMID: 26833096 (View on PubMed)

Scott CE, Clement ND, MacDonald DJ, Hamilton DF, Gaston P, Howie CR, Burnett R. Five-year survivorship and patient-reported outcome of the Triathlon single-radius total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. 2015 Jun;23(6):1676-83. doi: 10.1007/s00167-014-2922-8. Epub 2014 Mar 13.

Reference Type RESULT
PMID: 24623184 (View on PubMed)

Martin A, Quah C, Syme G, Lammin K, Segaren N, Pickering S. Long term survivorship following Scorpio Total Knee Replacement. Knee. 2015 Jun;22(3):192-6. doi: 10.1016/j.knee.2015.01.007. Epub 2015 Mar 26.

Reference Type RESULT
PMID: 25818502 (View on PubMed)

Other Identifiers

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CR17-003

Identifier Type: -

Identifier Source: org_study_id

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