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Study on Prenatal Diagnosis and Closed-loop Management System of Congenital Talipes Equinovarus

NCT ID: NCT05638490

Last Updated: 2022-12-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-08-03

Study Completion Date

2025-12-31

Brief Summary

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The study intends to establish a closed-loop management from prenatal to postnatal through prospective cohort, and comprehensively utilize ultrasound and MRI technology to establish a prenatal diagnosis and evaluation system for congenital talipes equinovarus. On the basis of existing genetic testing, further use of whole-exome sequencing and other genomic methods to explore possible pathogenic genes and loci, and clarify the pathogenic mechanism of congenital talipes equinovarus. Therefore, congenital talipes equinovarus can improve its diagnosis and treatment capacity, reduce the disability rate related to congenital talipes equinovarus, and prevent it well.

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Detailed Description

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Conditions

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Prenatal Diagnosis and Closed-loop Management System of Congenital Talipes Equinovarus

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1）Single pregnant women 2) "congenital talipes equinovarus" suggested by ultrasound

Exclusion Criteria

Twin or multiple pregnancies
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

OTHER

Sponsor Role lead

Responsible Party

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Zhu Xiangyu

Deputy director xiangyu zhu

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Drum Tower hospital

Nanjing, Jiangsu, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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xiangyu zhu, doctor

Role: primary

[email protected]
13951005854

Other Identifiers

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CTE-V1.0

Identifier Type: -

Identifier Source: org_study_id

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